Isolation and Characterization of Bioactive Metabolites form Marine-Derived Filamentous Fungi Collected from Tropical and Sub-Tropical Coral Reefs

Michio NAMIKOSHI; Hisayoshi KOBAYASHI; Takeshi YOSHIMOTO; Shiori MEGURO; Kyoko AKANO

doi:10.1248/cpb.48.1452

Michio NAMIKOSHI, Hisayoshi KOBAYASHI, Takeshi YOSHIMOTO, Shiori MEGURO, Kyoko AKANO

Author information

Keywords: bioactive metabolite, paecilospirone, marine fungi, isolation, phomopsidin, marine natural product

JOURNAL FREE ACCESS

2000 Volume 48 Issue 10 Pages 1452-1457

DOI https://doi.org/10.1248/cpb.48.1452

Details

Abstract

Two new compounds, paecilospirone (1) and phomopsidin (2), and seven known compounds, chaetoglobosin A (3), griseofulvin (4), fusarielin A (5), fusapyrone (6), deoxyfusapyrone (7), and verrucarins J (8) and L acetate(9), have been isolated and characterized from marine-derived fungi collected in tropical and sub-tropical coral reef environments. The utility of marine-derived fungi as a source of bioactive secondary metabolites is discussed.

Corresponding author

Register with J-STAGE for free!