Magnesium and Ammonium-Potassium Lithospermates B, the Active Principles Having a Uremia-Preventive Effect from Salvia miltiorrhiza

Takashi TANAKA; Satoshi MORIMOTO; Gen-ichiro NONAKA; Itsuo NISHIOKA; Takako YOKOZAWA; Hae Young CHUNG; Hikokichi OURA

doi:10.1248/cpb.37.340

Takashi TANAKA, Satoshi MORIMOTO, Gen-ichiro NONAKA, Itsuo NISHIOKA, Takako YOKOZAWA, Hae Young CHUNG, Hikokichi OURA

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Keywords: Salviae miltiorrhizae Radix, Labiatae, lithospermic acid B, magnesium lithospermate B, ammonium-potassium lithospermate B, uremic rat, uremia-preventive effect

JOURNAL FREE ACCESS

1989 Volume 37 Issue 2 Pages 340-344

DOI https://doi.org/10.1248/cpb.37.340

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Abstract

The active components which exhibit the improving effect on uremic symptoms have been isolated from Salviae miltriorrhizae Radix and characterized as magnesium lithospermate (1) and ammonium-potassium lithospermate (2). The stereostructure of lithospermic acid, which had remained unclarified, was also determined on the basis of chemical and spectroscopic data.

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