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Cleavage of Compounds from Solid Phase by Gaseous Reagents

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Combinatorial Library

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 201))

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Abstract

The recent interest in organic solid phase synthesis, triggered by the advent of chemical combinatorial methods (1–7), also accelerated methodology development. Simplification of chemical protocols, their robustness, and amenability to handling large arrays of compounds, prepared by combinatorial/ parallel solid phase synthesis, is one area that witnessed numerous novel contributions. This chapter describes an apparatus and method for gaseous cleavage of compounds from solid phase supports.

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Author information

Authors and Affiliations

  1. Encore International Corporation, Tucson, AZ

    Viktor Krchňák

Authors
  1. Viktor Krchňák
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Editor information

Editors and Affiliations

  1. BD Biosciences, San Jose, California

    Lisa Bellavance English

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© 2002 Humana Press Inc.

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Krchňák, V. (2002). Cleavage of Compounds from Solid Phase by Gaseous Reagents. In: English, L.B. (eds) Combinatorial Library. Methods in Molecular Biology™, vol 201. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-285-6:61

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  • DOI: https://doi.org/10.1385/1-59259-285-6:61

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-980-3

  • Online ISBN: 978-1-59259-285-2

  • eBook Packages: Springer Protocols

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