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Long-term stability of 6-hydroxymelatonin sulfate in 24-h urine samples stored at −20°C

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Abstract

The purpose of the present feasibility study was to determine whether the concentration of 6-hydroxymelatonin sulfate (6-OHMS) remains stable in urine samples stored over at least 15 yr. To test this, 117 twenty-four-hour urine samples were analyzed, which were obtained from healthy children ages 8 to 9 yr within the periods of 1985–1987, 1991–1993, and 1997–1999. 6-OHMS concentrations were determined by enzyme-linked immunosorbent assay. The statistical analyses clearly indicate that the concentration of 6-OHMS remains stable for at least 15 yr if the urine is stored at −20°C.

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Authors and Affiliations

  1. Institute for Occupational Physiology at the University of Dortmund, Ardeystr. 67, D-44139, Dortmund, Federal Republic of Germany

    Barbara Griefahn, Meinolf Blaszkewicz & Peter Bröde

  2. Research Institute of Child Nutrition Dortmund, Dortmund, Federal Republic of Germany

    Thomas Remer

Authors
  1. Barbara Griefahn
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  2. Thomas Remer
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  3. Meinolf Blaszkewicz
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  4. Peter Bröde
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Correspondence to Barbara Griefahn.

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Griefahn, B., Remer, T., Blaszkewicz, M. et al. Long-term stability of 6-hydroxymelatonin sulfate in 24-h urine samples stored at −20°C. Endocr 15, 199–202 (2001). https://doi.org/10.1385/ENDO:15:2:199

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  • DOI: https://doi.org/10.1385/ENDO:15:2:199

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