The cell wall as a mediator of the pathogenic activity of fungi of the genus Candida sp.

Enoktaeva O.V., Nikolenko M.V., Trushnikov D.Yu., Baryshnikova N.V.

Tyumen State Medical University of the Ministry of Health of the Russian Federation

The study of the chemical composition of the cell wall of fungi of the genus Candida sp. is an actual trend in modern medicine, allowing the development of new methods for the treatment of candidiasis. The polysaccharides mannan, glucan, and chitin form the framework of the cell wall, inside and on the surface of which proteins and other molecules are present. The components of the cell wall perform a wide range of functions: protect the contents of the cell from external factors; provide nutrition, respiration, reproduction and formation of cells of various morphologies; mediate the pathogenic properties of fungi, including biofilm formation, spread, and the ability to modulate the host's immune response.