Features of broncho-obstructive syndrome therapy in children

Fayzullina R.M., Shangareeva Z.A., Sannikova A.V., Mananova A.F., Shaverskaya A.G., Khamova M.S., Astafurova O.A.

Bashkir State Medical University, Ministry of Health of the Russian Federation, Ufa
GBUZ RB City Children's Clinical Hospital №17, Ufa

Aim. Тo evaluate the effectiveness of therapy for broncho-obstructive syndrome in children with asthma.
Materials and methods. The study included 135 children with signs of acute respiratory failure during exacerbation of asthma. The studied indicators (clinical-anamnestic, laboratory-instrumental) were analyzed using the Statistica 10.0 program.
Results. The analysis performed revealed the manifestation of asthma at the age of 3 [1; 5 years. Viral infection in 74.81 % (n = 101) and physical activity in 40.00 % (n = 54) of children were the main triggers of the disease. According to Friedman's rank analysis of variance and Kendall's concordance, dynamic observation demonstrated relief of clinical symptoms in children with exacerbation of asthma on days 1-3 (χ2 = 1904.051; p < 0) of nebulizer bronchodilator therapy.
Conclusion. The results of the study indicate the role of viral infection and physical activity in the exacerbation of asthma in children. Relief of clinical symptoms occurred on 1-3 days from the start of the ongoing nebulizer bronchodilator therapy.