An efficient and convenient protocol for the synthesis of optically active [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives containing L-amino acid moieties

Naesr Foroughifar; Sattar Ebrahimi; Akbar Mobinikhaledi; Reza Mozafari

doi:10.1515/HC.2011.048

Open Access Published by De Gruyter December 1, 2011

An efficient and convenient protocol for the synthesis of optically active [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives containing L-amino acid moieties

Naesr Foroughifar , Sattar Ebrahimi , Akbar Mobinikhaledi and Reza Mozafari

From the journal Heterocyclic Communications

https://doi.org/10.1515/HC.2011.048

Abstract

New triazolothiadiazoles bearing L-amino acid moieties were synthesized by reaction of 4-amino-5-phenoxy-4H-1,2,4-triazole-3-thiol with L-amino acids in the presence of phosphorus oxychloride.

Keywords: carbonothioic dihydrazide; L-amino acid; optical activity; phosphorus oxychloride; 1,2,4-triazole-3-thiol; triazolothiadiazole

Corresponding author

Received: 2011-7-28

Accepted: 2011-11-25

Published Online: 2011-12-01

Published in Print: 2011-12-01

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

An efficient and convenient protocol for the synthesis of optically active [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives containing L-amino acid moieties

Abstract

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