Abstract
Cadmium(II) is an omnipresent environmental toxicant emitted from various industrial sources and by anthropogenic sources such as smoking. Cadmium(II) enters our body through various sources including contaminated food and drinks and from active or passive smoking. It spares no organs in our body and the calamities it invites include primarily nephrotoxicity, osteotoxicity, teratogenicity, endocrine disruption, hepatotoxicity and carcinogenicity above all. It brings about a bolt from the blue in the cellular biochemistry by generating reactive oxygen species (ROS), disrupting the factors involved in the repair of DNA lesions and many other toxic nuisances otherwise by modulating the cell signalling machinery and acting as a potent carcinogen above all. In this review, we have tried to decipher some of the mechanisms played by cadmium(II) in exhibiting its toxic effects on various system of our body.
Funding source: Council of Scientific and Industrial Research, India
Award Identifier / Grant number: 08/463(0001)/2019-EMR-1
Acknowledgments
We would like to thank all the faculties of the Department of Microbiology, University of Calcutta for their valuable suggestions for the betterment of our work.
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Research funding: The work was funded by Council of Scientific & industrial Research (Award Letter no. 08/463(0001)/2019-EMR-1), Dated: 7/12/2019
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: Not Applicable.
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Ethical approval: Not Applicable.
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