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Licensed Unlicensed Requires Authentication Published by De Gruyter December 13, 2010

Twin-to-twin transfusion syndrome (TTTS)*

  • WAPM consensus group on Twin-to-twin transfusion syndrome , Ahmet Baschat , Ramen H. Chmait , Jan Deprest , Eduard Gratacós EMAIL logo , Kurt Hecher , Efficia Kontopoulos , Ruben Quintero , Daniel W. Skupski , Dan V. Valsky and Yves Ville

Abstract

Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies, characterized by the development of unbalanced chronic blood transfer from one twin, defined as donor twin, to the other, defined as recipient, through placental anastomoses. If left untreated, TTTS is associated with very high perinatal mortality and morbidity rates, due to a combination of fetal and/or obstetric complications. The reported prevalence is 10–15% of all MC twins, or about 1 in 2000 pregnancies. This consensus document reviews available evidence and offers practical guidance to clinicians by providing recommendations on various aspects concerning diagnosis and management of TTTS.


Corresponding author: Eduard Gratacós Department of Maternal-Fetal Medicine Institut Clínic de Ginecologia Obstetrícia i Neonatologia Hospital Clinic-IDIBAPS University of Barcelona and CIBERER Barcelona Spain

Published Online: 2010-12-13
Published Online: 2011-01-13
Published in Print: 2011-03-01

©2011 by Walter de Gruyter Berlin New York

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