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Licensed Unlicensed Requires Authentication Published by De Gruyter June 2, 2014

Interaction between the Peroxide Adduct of Binuclear Iron(III) Complex with (HPTP) Anion and the Sugar Moiety of Nucleosides

  • Satoshi Nishino , Mami Kunita , Teruyuki Kobayashi , Hideaki Matsushima , Tadashi Tokii and Yuzo Nishida EMAIL logo

We have in this study obtained the experimental evidence to suggest that the peroxide adduct of binuclear iron(III) complex with H(HPTP) directly reacts with the sugar moiety of the DNA chain, to cleave it; H(HPTP) denotes N,N,N′,N′-tetrakis(2-pyridylmethyl)-1,3-diamino- 2 -propanol.

Received: 1999-2-15
Published Online: 2014-6-2
Published in Print: 1999-10-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

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