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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Indole Alkaloids from Cell Suspension Cultures of Stemmadenia tomentosa and Voacanga africana

  • Joachim Stöckigt , Karl-Heinz Pawelka , Ana Rother and Brigitte Deus

Abstract

Cell suspension cultures of Stemmadenia tomentosa synthesized under normal growth condition the eight major indole alkaloids: (-)-tabersonine, (-)-minovincinine, (+)-conoflorine (voaphyl-line), condylocarpine, (+)-tubotaiwine (dihydrocondylocarpine), (-)-norfluorocurarine (vin-canine), (-)-vinervine, and (-)-coronaridine. These alkaloids consist of the three different types, Aspidosperma, Strychnos and Iboga. In contrast, cultures o f Voacanga africana produced mainly one alkaloid group (Aspidosperma-type) represented by (-)-tabersonine, lochnericine and (-)-minovincinine. Therefore this cell culture seems to be qualified for investigation concerning the biosynthesis of Aspidosperma alkaloids.

Received: 1982-6-3
Published Online: 2014-6-2
Published in Print: 1982-10-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

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