Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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A Study on the Effectiveness of a Mixed Fermented Extract of Vitamin Tree Fruit, Acai Palm Fruit, Mango, Lemon, Apricot and Blueberry as an Active Ingredient

비타민나무열매, 아사이팜열매, 망고, 레몬, 살구 및 블루베리의 혼합 발효추출물의 효능 연구

  • 김수창 (그린코스 주식회사 중앙연구소) ;
  • 이미래 (그린코스 주식회사 중앙연구소) ;
  • 조원표 (그린코스 주식회사 중앙연구소) ;
  • 윤여필 (그린코스 주식회사 중앙연구소)
  • Received : 2022.08.19
  • Accepted : 2022.09.27
  • Published : 2022.09.30
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Abstract

In this study, the cell viability, radical scavenging ability, elastase activity, moisturizing activity, and antimicrobial activity of mixed fermented extract of vitamin tree fruit, acai palm fruit, mango, lemon, apricot and blueberry as an active ingredient were measured. The experiment was performed at three concentrations(0.5 / 1.5 / 2%), since cytotoxicity was not shown at these three concentrations. Based on this, a radical scavenging experiment was conducted to compare with L-ascorbic acid, a representative raw material of an antioxidant material. The results showed that the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging ability was 95.1 ± 0.6%, 94.3 ± 0.7%, 95.3 ± 0.6%, 95.1 ± 0.7%, 95.1 ± 0.3%, 95.5 ± 0.3%, and 95.4 ± 0.4% respectively, when the concentration of the mixed fermentation extract was 2%. As the concentration increased at the three concentrations (0.5/1.5/2%) and the content of blueberry extracts increased, sample 7 showed excellent elastase activity at a concentration of 2% to 0.9 cm, such as retinol crystal, and moisturizing activity was also found to be 71.5%, 75.6%, and 81.6%, respectively. Particularly, at the 2% concentration of the mixed fermented extract, the antibacterial activity effect on Propionibacterium was very excellent in sample 7. Therefore, it is considered that it is worth developing the mixed fermented extracts of 2% concentration as a cosmetic component with antioxidant, moisturizing, and antibacterial properties.

본 연구는 비타민나무열매, 아사이팜열매, 망고, 레몬, 살구 및 블루베리의 혼합 발효물이 화장품 소재로서의 가능성을 확인하기 위하여 세포독성, 라디칼 소거 능력, 엘라스타아제, 보습, 항균 활성 측정을 수행 및 확인하였다. 혼합 발효추출물의 세 농도(0.5 / 1.5 / 2%)에서 세포독성을 보이지 않아 해당 농도로 실험을 수행하였다. 이를 바탕으로 항산화 소재의 대표적 원료인 L-ascorbic acid와 비교하는 라디칼 소거능 실험을 실시하였다. 그 결과 1,1-diphenyl-2-picrylhydrazyl (DPPH) 라디칼 소거능력은 혼합 발효추출물의 농도가 2%일 때, Sample 1 ~ 7은 각각 95.1 ± 0.6%, 94.3 ± 0.7%, 95.3 ± 0.6%, 95.1 ± 0.7%, 95.1 ± 0.3%, 95.5 ± 0.3%, 그리고 95.4 ± 0.4% 로 우수한 항산화 능력을 확인하였다. 세 농도(0.5 / 1.5 / 2%)에서 농도의 증가와 블루베리추출물의 함량이 증가함에 따라 sample 7은 2% 농도에서 대조예인 retinol crystal과 같은 0.9 cm로 엘라스타제 활성이 우수함을 알 수 있었으며, 보습 활성 또한 HAS-3 증가율이 세 농도에서 각각 71.5%, 75.6%, 81.6%로 우수한 결과를 확인하였다. 항균 활성은 혼합 발효추출물의 농도가 0.5%에서 2%로 증가, 블루베리 함량의 증가에 따라서 우수한 항균 활성을 확인하였다. 특히, 혼합 발효추출물의 농도가 2%에서 sample 7에서 프로피오니박테리움(Propionibacterium)에 대한 항균 활성 효과가 매우 우수한 것을 확인하였다. 따라서 혼합 발효추출물 2%의 농도에서 항산화, 보습, 항균성을 가지는 화장품 성분으로서 개발가치가 충분하다고 사료된다.

Keywords

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