Internalization, Intracellular Trafficking, Biodistribution of Monoclonal Antibody 806: A Novel Anti-Epidermal Growth Factor Receptor Antibody1,2
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open access
Keywords
Internalization
epidermal growth factor receptor
intracellular trafficking
dynamin
monoclonal antibody
Abbreviations
Cy3
cyanine 3
EEA1
early endosome autoantigen 1
EGFR
epidermal growth factor receptor
FITC
fluorescein isothiocyanate
GFP
green fluorescent protein
LAMP1
lysosomal-associated membrane protein 1
mAb
monoclonal antibody
PFA
paraformaldehyde
Tfn
transferrin
Cited by (0)
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This work was partly supported by the National Health and Medical Research Council of Australia (Program Grant 280912), the Human Frontier Science Program (Young Investigator Award RGY40/2003), Bayer Pharmaceuticals Scholar Award, the Ludwig Institute for Cancer Research (to D.T), a Boehringer Ingelheim Fonds PhD Scholarship (to R.Z.).
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This article refers to supplementary materials, which are designated by Figure W1 and Videos W1 to W5 and are available online at www.neoplasia.com.
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Current address: Department of Cell Biology, Yale University School of Medicine, SHM C229, 333 Cedar Street, New Haven, CT 06520, USA.
Copyright © 2007 Neoplasia Press, Inc. Published by Elsevier Inc.