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Construction and utilization of human genetic resources in large population cohortsChinese Full TextEnglish Full Text (MT)

Xingdong Chen;Yanfeng Jiang;Ping Xu;Li Jin;State Key Laboratory of Genetic Engineering, Human Phenome Institute, School of Life Sciences, Fudan University;Fudan University Taizhou Institute of Health Sciences;Shanghai Information Center for Life Sciences, Chinese Academy of Sciences;Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences;

Abstract: In the era of big data and precision medicine, large population cohort studies are one of the preferred designs for studying the etiology of chronic diseases, and cohort genetic resources have become important strategic resources of China. Promoting the standardized construction and utilization of cohort genetic resources can effectively promote the original innovation of research and technological development in the field of biomedicine, and make full use of the rich genetic resources of China. To provide a reference for the construction and utilization of genetic resources in the cohort research in China, we took the Taizhou Longitudinal Study(TZL) as an example and introduced the principles, methods,standard system, and practical experience of the collection, preservation, and shared utilization of genetic resources in the process of the cohort construction.
  • DOI:

    10.16288/j.yczz.21-195

  • Series:

    (A) Mathematics/ Physics/ Mechanics/ Astronomy

  • Subject:

    Biology

  • Classification Code:

    Q987

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