Vet Med - Czech, 2009, 54(3):97-110 | DOI: 10.17221/50/2009-VETMED

Induction of final oocyte maturation in Cyprinidae fish by hypothalamic factors: a review

P. Podhorec, J. Kouril
University of South Bohemia, Research Institute of Fish Culture and Hydrobiology, Vodnany, Czech Republic

Gonadotropin-releasing hormone in Cyprinidae as in other Vertebrates functions as a brain signal which stimulates the secretion of luteinizing hormone from the pituitary gland. Two forms of gonadotropin-releasing hormone have been identified in cyprinids, chicken gonadotropin-releasing hormone II and salmon gonadotropin-releasing hormone. Hypohysiotropic functions are fulfilled mainly by salmon gonadotropin-releasing hormone. The only known factor having an inhibitory effect on LH secretion in the family Cyprinidae is dopamine. Most cyprinids reared under controlled conditions exhibit signs of reproductive dysfunction, which is manifested in the failure to undergo final oocyte maturation and ovulation. In captivity a disruption of endogenous gonadotropin-releasing hormone stimulation occurs and sequentially that of luteinizing hormone, which is indispensible for the final phases of gametogenesis. In addition to methods based on the application of exogenous gonadotropins, the usage of a method functioning on the basis of hypothalamic control of final oocyte maturation and ovulation has become popular recently. The replacement of natural gonadotropin-releasing hormones with chemically synthesized gonadotropin-releasing hormone analogues characterized by amino acid substitutions at positions sensitive to enzymatic degradation has resulted in a centuple increase in the effectiveness of luteinizing hormone secretion induction. Combining gonadotropin-releasing hormone analogues with Dopamine inhibitory factors have made it possible to develop an extremely effective agent, which is necessary for the successful artificial reproduction of cyprinids.

Keywords: reproductive dysfunction; ovulation; luteinizing hormone; gonadotropin-releasing hormone; gonadotropin; dopamine; dopamine antagonist; cyprinids

Published: March 31, 2009  Show citation

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Podhorec P, Kouril J. Induction of final oocyte maturation in Cyprinidae fish by hypothalamic factors: a review. Vet Med-Czech. 2009;54(3):97-110. doi: 10.17221/50/2009-VETMED.
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    References

    1. Abraham M. (1988): Recent trends in research on induced spawning of fish in aquaculture. Journal of Applied Ichtyology, 4, 49-64. Go to original source...
    2. Adams B.A., Vickers E.D., Warby C., Park M., Fischer W.H., Grey Craig A., Rivier J.E., Sherwood N.M. (2002): Three forms of gonadotropin-releasing hormone, including a novel form, in a basal salmonid, Coregonus clupeaformis. Biology of Reproduction, 67, 232-239. Go to original source... Go to PubMed...
    3. Alok D., Pillai D., Garg L.C. (1997): Effect of d-Lys6 salmon sGnRH alone and in combination with domperidone on the spawning of common carp during the late spawning season. Aquaculture International, 5, 369-374. Go to original source...
    4. Alvarez-Lajonchere L., Guerrero-Tortolero D., PerezUrbiola J.C. (2001): Validation of an ovarian biopsy method in a sea bass, Centropomus medius Gunther. Aquaculture Research, 32, 379-384. Go to original source...
    5. Arabaci M., Sari M. (2004): Induction of ovulation in endemic pearl mullet (Chalcalburnus tarichi), living in the highly alkaline Lake Van, using GnRHa ([DSer(tBu6), Pro9-Net]-GnRH) combined with haloperidol. Aquaculture, 238, 529-535. Go to original source...
    6. Arabaci M., Cegirgan H., Sari M. (2004): Induction of ovulation in ornamental common carp (Koi, Cyprinus carpio L.) using LHRHa ([D-Ser(tBu6), Pro9-Net]LHRH) combined with haloperidol and carp pituitary extract. Aquaculture Research, 35, 10-14. Go to original source...
    7. Blomenrohr M., Bogerd J., Leurs R., Schulz R.W., Tensen C.P., Zandbergen M.A., Goos H.J.Th. (1997): Differences in structure-function relations between nonmammalian and mammalian gonadotropin-releasing hormone receptors. Biochemical and Biophysical Research Communications, 238, 517-522. Go to original source... Go to PubMed...
    8. Blomenrohr M., Goos H., Bogerd J. (2005): GnRH receptors in Fish: Differences in structure-function relations between mammalian and non-mammalian GnRH receptors. 40-75. In: Melamed P., Sherwood N. (eds.): Hormones and their Receptors in Fish Reproduction. World Scientific Publishing, Singapore. 297 pp. Go to original source...
    9. Bogerd J., Li K.W., Janssen-Dommerholt C., Goos H. (1992): Two gonadotropin-releasing hormones from African catfish (Clarias gariepinus). Biochemical and Biophysical Research Communications, 187, 127- 134. Go to original source... Go to PubMed...
    10. Breton B., Weil C. (1973): Effets du LH/FSH-RU synthetique et d´extraits hypothalamiques de carpe sur la secretion d´ hormone gonadotrope in vivo Cheb la carp (Cyprinus carpio L.). C.R. Academia Scie. Paris, 27, 2061-2064.
    11. Breton B., Roelants Y., Ollevier F., Epler P., Mikolajczyk T. (1998): Improved bioavailability of orally delivered peptides and polypeptides in teleost fish. Journal of Applied Ichtyology, 14, 251-257. Go to original source...
    12. Brzuska E. (1999): Artificial spawning of herbivorous fish: use of an LHRH-a to induce ovulation in grass carp Ctenopharyngodon idella (Valenciennes) and silver carp Hypophthalmichthys molitrix (Valenciennes). Aquaculture Research, 30, 849-856. Go to original source...
    13. Brzuska E. (2006): Artificial propagation of female Hungarian strain 7 carp (Cyprinus carpio) after treatment with carp pituitary homogenate, Ovopel or Dagin. Czech Journal of Animal Science, 51, 132-141. Go to original source...
    14. Burgus R., Butcher M., Ling N., Monahan M., Rivier J., Fellows R., Amoss M., Blackwell R., Vale W., Guillemin R. (1971): Molecular structure of the hypothalamic factor (LRF) of ovine origin monitoring the secretion of pituitary gonadotropic hormone of luteinization (LH). Comptes rendus hebdomadaires des séances de l'Académie des sciences. Serie D: Sciences Naturelles, 273, 1611-1613.
    15. Carolsfeld J., Powell J.F., Park M., Fischer W.H., Craig A.G., Chang J.P., Rivier J.E., Sherwood N.M. (2000): Primary structure and function of three gonadotropin-releasing hormones, including a novel form, from an ancient teleost, herring. Endocrinology, 141, 505-512. Go to original source... Go to PubMed...
    16. Chang J.P., Jobin R.M., Wong A.O. (1993): Intracellular mechanisms mediating gonadotropin and growth hormone release in the goldfish, Carassius auratus. Fish Physiology and Biochemistry, 11, 25-33. Go to original source... Go to PubMed...
    17. Chen C.-C., Fernald R.D. (2008): GnRH and GnRH receptors: distribution, function and evolution. Journal of Fish Biology, 73, 1099-1120. Go to original source...
    18. Cyr D.G., Eales J.G. (1996): Interrelationships between thyroidal and reproductive endocrine systems in fish. Reviews in Fish Biology and Fisheries, 6, 165-200. Go to original source...
    19. De Leeuw R., Habibi H.R., Nahorniak C.S., Peter R.E. (1989): Dopaminergic regulation of pituitary gonadotrophin-releasing hormone receptor activity in the goldfish (Carassius auratus). Journal of Endocrinology, 121, 239-247. Go to original source... Go to PubMed...
    20. Directive of the European parliament and of the Council (2004): Directive 2004/28/EC of the European Parliament and of the Council of 31 March 2004 amending Directive 2001/82/EC on the Community code relating to veterinary medicinal products. Official Journal of the European Union, L136, 58-84.
    21. Drori S., Ofir M., Levavi-Sivan B., Yaron Z. (1994): Spawning induction in common carp (Cyprinus carpio) using pituitary extract or GnRH superactive analogue combined with metoclopramide: analysis of hormone profile, progress of oocyte maturation and dependence on temperature. Aquaculture, 119, 393-407. Go to original source...
    22. Dubois E.A., Zandbergen M.A., Peute J., Goos H.J. (2002): Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates. Brain Research Bulletin, 57, 413-418. Go to original source... Go to PubMed...
    23. Dufour S., Weltzien F.A., Sebert M.E., Le Belle N., Vidal B., Vernier P., Pasqualini C. (2005): Dopaminergic inhibition of reproduction in teleost fishes: ecophysiological and evolutionary implications. Annals of the New York Academy of Sciences, 1040, 9-21. Go to original source... Go to PubMed...
    24. Fermin A.C. (1991): LHRH-a and domperidone-induced oocyte maturation and ovulation in bighead carp, Aristichthys nobilis (Richardson). Aquaculture, 93, 87-94. Go to original source...
    25. Fernald R.D., White R.B. (1999): Gonadotropin-releasing hormone genes: phylogeny, structure, and functions. Frontiers in Neuroendocrinology, 20, 224-240. Go to original source... Go to PubMed...
    26. Garcia L.M.B. (1989): Development of an ovarian biopsy technique in the sea bass, Lates calcarifer (Bloch). Aquaculture, 77, 97-102. Go to original source...
    27. Glasser F., Mikolajczyk T., Jalabert B., Baroiller J.-F., Breton B. (2004): Temperature effects along the reproductive axis during spawning induction of grass carp (Ctenopharyngodon idella). General and Comparative Endocrinology, 136, 171-179. Go to original source... Go to PubMed...
    28. Habibi H.R., De Leeuw R., Nahorniak C.S., Th Goos H.J., Peter R.E. (1989): Pituitary gonadotropin-releasing hormone (GnRH) receptor activity in goldfish and catfish: seasonal and gonadal effects. Fish Physiology and Biochemistry, 7, 109-118. Go to original source... Go to PubMed...
    29. Hamackova J., Kouril J., Barth T., Lepicova A., Kozak P., Lepic P. (2001): Induction of ovulation in rudd (Scardinius erythrophthalmus) using hormone preparations. Collections Symposium Series, Institute of Organic Chemistry and Biochemistry of the ASCR, Prague, 4, 87-89. Go to original source...
    30. Heyrati F.P., Mostafavi H., Toloee H., Dorafshan S. (2007): Induced spawning of kutum, Rutilus frisii kutum (Kamenskii, 1901) using (D-Ala6, Pro9-NEt) GnRHa combined with domperidone. Aquaculture, 265, 288-293. Go to original source...
    31. Hill J.E., Baldwin J.D., Graves J.S., Leonard R., Powell J.F.F., Watson C.A. (2005): Preliminary observations of topical gill application of reproductive hormones for induced spawning of a tropical ornamental fish. North American Journal of Aquaculture, 67, 7-9. Go to original source...
    32. Illing N., Troskie B.E., Nahorniak C.S., Hapgood J.P., Peter R.E., Millar R.P. (1999): Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus). Proceedings of the National Academy of Sciences of the United States of America, 96, 2526-2531. Go to original source... Go to PubMed...
    33. Kah O., Chambolle P., Thibault J., Geffard M. (1984): Existence of dopaminergic-neurons in the preoptic region of the goldfish. Neuroscience Letters, 48, 293-298. Go to original source... Go to PubMed...
    34. Kah O., Lethimonier Ch., Somoza G., Guilguir L., Vaillant C., Lareyre J.J. (2007): GnRH and GnRH receptors in Metazoa: A historical, comparative and evolutive perspective. General and Comparative Endocrinolology, 153, 346-364. Go to original source... Go to PubMed...
    35. Kaminski R., Kusznierz J., Myszkowski L., Wolnicki J. (2004): The first attempt to artificially reproduce the endangered cyprinid lake minnow Eupallasella perenurus (Pallas). Aquaculture International, 12, 3-10. Go to original source...
    36. Karten M.J., Rivier J.E. (1986): Gonadotropin-releasing hormone analog design. Structure-function studies toward the development of agonists and antagonists: rationale and perspective. Endocrine Reviews, 7, 44-66. Go to original source... Go to PubMed...
    37. Kestemont P. (1988): Effects of hormonal treatments on induced ovulation in gudgeon, Gobio gobio L. Aquaculture, 68, 373-385. Go to original source...
    38. Kim M.H., Oka Y., Amano M., Kobayashi M., Okuzawa K., Hasegawa Y., Kawashima S., Suzuki Y., Aida K. (1995): Immunocytochemical localization of sGnRH and cGnRH-II in the brain of goldfish, Carassius auratus. The Journal of Comparative Neurology, 356, 72-82. Go to original source... Go to PubMed...
    39. Kobayashi M., Amano M., Kim M.H., Yoshiura Y., Sohn Y.C., Suetake H., Aida K. (1997): Gonadotropin-releasing hormone and gonadotropin in goldfish and masu salmon. Fish Physiology and Biochemistry, 17, 1-8. Go to original source...
    40. Kouril J., Barth T. (1981): Artificiall induction of ovulation by LH-RH in tench (Tinca tinca L.) (in Czech). Bulletin of Research Institute of Fish Culture and Hydrobiology, Vodnany, 17, 13-18.
    41. Kouril J., Chabera S. (1976): Artificiall spawning of tench (Tinca tinca L.) (in Czech). Bulletin VURH Vodnany, 12, 7-13.
    42. Kouril J., Barth T., Hamackova J., Flegel M. (1986): Induced ovulation in tench (Tinca tinca L.) by various LH-RH synthetic analogues: effect of site of administrative and temperature. Aquaculture, 54, 37-44. Go to original source...
    43. Kouril J., Hamackova J., Barth T., Hulova I., Barthova J. (1999): Artificial stripping of large mouth buffalo (Ictiobus cyprinellus) using carp pituitary, GnRH analog and dopaminergic inhibitor isofloxythepin. Biologically Active Peptides VI, Collection Symposium Series, Prague, 3, 68-70. Go to original source...
    44. Kouril J., Hamackova J., Barth T. (2006): Hormonally induce artificiall reproduction of fish (in Czech). Biotechnology 2006, Scientific Pedagogical Publishing, Ceske Budejovice, Czech Republic, 251-253.
    45. Kouril J., Svoboda A., Hamackova J., Kalab P., Kolarova J., Lepicova A., Sedova M., Savina L., Rendon P.M., Svobodova Z., Barth T., Vykusova B. (2007): Repeated administration of different hormonal preparations for artificial propagation and their effects on reproduction, survival and blood biochemistry profiles of female tench (Tinca tinca L.). Czech Journal of Animal Science, 52, 183-188. Go to original source...
    46. Kouril J., Mraz J., Hamackova J., Barth T. (2008): Hormonal induction of tench (Tinca tinca L.) with the same treatments at two sequential reproductive seasons. Cybium, 32, 61.
    47. Krejszeff S., Kucharczyk D., Kupren K., Targonska K., Mamcarz A., Kujawa R., Kaczkowski Z., Ratajski S. (2008): Reproduction of chub, Leuciscus cephalus L., under controlled conditions. Aquaculture Research, 39, 907-912. Go to original source...
    48. Kroupova H., Machova J., Svobodova Z. (2005): Nitrite influence on fish: a review. Veterinarni Medicina, 50, 461-471. Go to original source...
    49. Kucharczyk D., Kujawa R., Mamcarz A., Targonska-Dietrich K., Wyszomirska E., Glogowski J., Babiak I., Szabo T. (2005): Induced spawning in bream (Abramis brama) using pellets containing GnRH. Czech Journal of Animal Science, 3, 89-95. Go to original source...
    50. Lam T.J., Pandey S., Hoar W.S. (1975): Induction of ovulation in goldfish by synthetic luteinizing hormonereleasing hormone (LHRH). Canadian Journal of Zoology, 53, 1189-1192. Go to original source... Go to PubMed...
    51. Le Gac F., Blaise O., Fostier A., Le Bail P.Y., Loir M., Mourot B., Weil C. (1993): Growth hormone (GH) and reproduction: A review. Fish Physiology and Biochemistry, 11, 219-232. Go to original source... Go to PubMed...
    52. Lethimonier C., Madigou T., Munoz-Cueto J.A., Lareyre J.J., Kah O. (2004): Evolutionary aspects of GnRHs, GnRH neuronal systems and GnRH receptors in teleost fish. General and Comparative Endocrinology, 135, 1-16. Go to original source... Go to PubMed...
    53. Levavi-Zermonsky B., Yaron Z. (1986): Changes in gonadotropin and ovarian steroids associated with oocytes maturation during spawning induction in the carp. General and Comparative Endocrinology, 62, 89-98. Go to original source... Go to PubMed...
    54. Lin X.W., Peter R.E. (1997): Cloning and expression pattern of a second [His(5)Trp(7)Tyr(8)] gonadotropinreleasing hormone (chicken GnRH-II) mRNA in goldfish: Evidence for two distinct genes. General and Comparative Endocrinology, 107, 262-272. Go to original source...
    55. Lin H.R., Kraak G.V.D., Liang J.Y., Peng C., Li G.Y., Lu L.Z., Zhou X.-J., Chang M.L., Peter R.E. (1986): The effects of LHRH analogue and drugs which block the effects of dopamine on gonadotropin secretion and ovulation in fish cultured in China. 139-150. In: Billard R., Marcel J. (eds.): Aquaculture of Cyprinids. INRA, Paris. 502 pp.
    56. Mananos E., Duncan N., Mylonas C. (2009): Reproduction and control of ovulation, spermiation and spawning in cultured fish. 3-80. In: Cabrita E., Robles V., Herraez P. (eds.): Methods in Reproductive Aquaculture: Marine and Freshwater Species. CRC Press, Florida. 549 pp. Go to original source...
    57. Linhart O., Peter R.E., Rothbard S., Zohar Y., Kvasnicka P. (1995): Spermiation of common tench (Tinca tinca L.) stimulated with injection or implantation of GnRH analogues and injection of carp pituitary extract. Aquaculture, 129, 119-121. Go to original source...
    58. Matsuda K., Nakamura K., Shimakura S.I., Miura T., Kageyama H., Uchiyama M., Shioda S., Ando H. (2008): Inhibitory effect of chicken gonadotropin-releasing hormone II on food intake in the goldfish, Carassius auratus. Hormones and Behavior, 54, 83-89. Go to original source... Go to PubMed...
    59. Matsuo H., Baba Y., Nair R.M., Arimura A., Schally A. V. (1971): Structure of the porcine LH- and FSH-releasing hormone I. The proposed amino acid sequence. Biochemical and Biophysical Research Communications, 43, 1334-1339. Go to original source... Go to PubMed...
    60. Mikolajczyk T., Roelants I., Epler P., Ollevier F., Schulz R.W.S., Sokolowska-Mikolajczyk M., Breton B. (2001): Assessment of tissue damaging effects of mixed micellar absorption enhancers on the intestinal mucosa of common carp (Cyprinus carpio), African catfish (Clarias gariepinus) and rainbow trout (Oncorhynchus mykiss) as a consequence of enhanced intestinal absorption of sGnRH-a. Journal of Applied Ichtyology, 17, 267-272. Go to original source...
    61. Mikolajczyk T., Chyb J., Sokolowska-Mikolajczyk M., Enright W.J., Epler P., Filipiak M., Breton B. (2003): Attempts to induce an LH surge and ovulation in common carp (Cyprinus carpio L.) by differential application of a potent GnRH analogue, azagly-nafarelin, under laboratory, commercial hatchery and natural conditions. Aquaculture, 223, 141-157. Go to original source...
    62. Mikolajczyk T., Chyb J., Szczerbik P., Sokolowska-Mikolajczyk M., Epler P., Enright W.J., Filipiak M., Breton B. (2004): Evaluation of the potency of azagly-nafarelin (GnRH analogue), administered in combination with different formulations of pimozide, on LH secretion, ovulation and egg quality in common carp (Cyprinus carpio L.) under laboratory, commercial hatchery and natural conditions. Aquaculture, 234, 447-460. Go to original source...
    63. Millar R.P., Lu Z.L., Pawson A.J., Flanagan C.A., Morgan K., Maudsley S.R. (2004): Gonadotropin-releasing hormone receptors. Endocrine Reviews, 25, 235- 275. Go to original source... Go to PubMed...
    64. Missale C., Nash S.R., Robinson S.W., Jaber M., Caron M.G. (1998): Dopamine receptors: from structure to function. Physiological Reviews, 78, 189-225. Go to original source... Go to PubMed...
    65. Montaner A.D., Park M.K., Fischer W.H., Craig A.G., Chang J.P., Somoza G.M., Rivier J.E., Sherwood N.M. (2001): Primary structure of a novel gonadotropinreleasing hormone in the brain of a teleost, Pejerrey. Endocrinology, 142, 1453-1460. Go to original source... Go to PubMed...
    66. Mylonas C.C., Zohar Y. (2001a): Endocrine regulation and artificial induction of oocyte maturation and spermiation in basses of the genus Morone. Aquaculture, 202, 205-220. Go to original source...
    67. Mylonas C.C., Zohar Y. (2001b): Use of GnRHa-delivery systems for the control of reproduction in fish. Reviews in Fish Biology and Fisheries, 10, 463-491. Go to original source...
    68. Mylonas C.C., Zohar Y. (2007): Promoting oocyte maturation, ovulation and spawning in farmed fish. 437- 474. In: Babin J.P., Cerda J., Lubzens E. (eds.): The Fish Oocyte. Springer, The Netherlands. 510 pp. Go to original source...
    69. Mylonas C.C., Scott A.P., Zohar Y. (1997): Plasma gonadotropin II, sex steroids, and thyroid hormones in wild striped bass (Morone saxatilis) during spermiation and final oocyte maturation. General and Comparative Endocrinology, 108, 223-236. Go to original source... Go to PubMed...
    70. Negatu Z., Hsiao S.M., Wallace R.A. (1998): Effects of insulin-like growth factor-I on final oocyte maturation and steroid production in Fundulus heteroclitus. Fish Physiology and Biochemistry, 19, 13-21. Go to original source...
    71. Nelson J.S. (2006): Fishes of the World. 4th ed. John Wiley and Sons, New York. 601 pp.
    72. Okubo K., Nagahama Y. (2008): Structural and functional evolution of gonadotropin-releasing hormone in vertebrates. Acta Physiologica, 193, 3-15. Go to original source... Go to PubMed...
    73. Omeljaniuk R.J., Shih S.H., Peter R.E. (1987): In-vivo evaluation of dopamine receptor-mediated inhibition of gonadotrophin secretion from the pituitary gland of the goldfish, Carassius auratus. Journal of Endocrinology, 114, 449-458. Go to original source... Go to PubMed...
    74. Osornio A.G., Chavez M., Peter E.R., Cardenas R. (2004): Quantification of the effects of resperine on gonadotroph expression in the pituitary of goldfish (Carassius auratus). Journal of Molecular Histology, 35, 417-420. Go to original source... Go to PubMed...
    75. Palevitch O., Kight K., Abraham E., Wray S., Zohar Y., Gothilf Y. (2007): Ontogeny of the GnRH systems in zebrafish brain: in situ hybridization and promoterreporter expression analyses in intact animals. Cell Tissue Research, 327, 313-322. Go to original source... Go to PubMed...
    76. Parhar S.I. (2003): Gonadotropin-releasing hormone receptors: neuroendocrine regulators and neuromodulators. Fish Physiology and Biochemistry, 28, 13-18. Go to original source...
    77. Penlington M.C., Williams M.A., Sumpter J.P., RandWeaver M., Hoole D., Arme C. (1997): Isolation and characterisation of mRNA encoding the salmon- and chicken-II type gonadotrophin-releasing hormones in the teleost fish Rutilus rutilus (Cyprinidae). Journal of Molecular Endocrinology, 19, 337-346. Go to original source... Go to PubMed...
    78. Peter R.E., Yu K.L. (1997): Neuroendocrine regulation of ovulation in fishes: basic and applied aspects. Reviews in Fish Biology and Fisheries, 7, 173-197. Go to original source...
    79. Peter R.E., Nahorniak C.S., Sokolowska M., Chang J.P., Rivier J.E., Vale W.W., King J.A., Millar R.P. (1985): Structure-activity relationships of mammalian, chicken, and salmon gonadotropin releasing hormones in vivo in goldfish. General and Comparative Endocrinology, 58, 231-242. Go to original source... Go to PubMed...
    80. Peter R.E., Chang J.P., Nahorniak C.S., Omeljaniuk R.J., Sokolowska M., Shih S.H., Billard R. (1986): Interactions of catecholamines and GnRH in regulation of gonadotropin secretion in teleost fish. Recent Progress in Hormone Research, 13, 229-239.
    81. Peter R.E., Lin H.R., Van Der Kraak G. (1988): Induced ovulation and spawning of cultured freshwater fish in China: advances in application of GnRH analogues and Dopamine antagonists. Aquaculture, 74, 1-10. Go to original source...
    82. Peter R.E., Trudeau V.L., Sloley B.D. (1991): Brain regulation of reproduction in teleosts. Bulletin of the Institute of Zoology, Academia Sinica, 16, 89-118.
    83. Pham K.X, Amano M., Amiya N., Kurita Y., Yamamori K. (2006): Distribution of three GnRHs in the brain and pituitary of the wild Japanese flounder Paralichthys olivaceus. Fisheries Science, 72, 89-94. Go to original source...
    84. Popesku T.J., Martyniuk J.C., Mennigen J., Xiong H., Zhang D., Xia X., Cossins R.A., Trudeau L.V. (2008): The goldfish (Carassius auratus) as a model for neuroendocrine signaling. Molecular and Cellular Endocrinology, 293, 43-56. Go to original source... Go to PubMed...
    85. Powell J.F.F., Zohar Y., Elizur A., Park M., Fischer W.H., Craig A.G., Rivier J.E., Lovejoy D.A., Sherwood N.M. (1994): Three forms of gonadotropin-releasing hormone characterized from brains of one species. Proceedings of the National Academy of Sciences of the United States of America, 91, 12081-12085. Go to original source... Go to PubMed...
    86. Powell J.F.F., Krueckl S.L., Collins P.M., Sherwood N.M. (1996): Molecular forms of GnRH in three model fishes: rockfish, medaka and zebrafish. Journal of Endocrinology, 150, 17-23. Go to original source... Go to PubMed...
    87. Roelants I., Mikolajczyk T., Epler P., Ollevier F., Chyb J., Breton B. (2000): Induction of spermiation in common carp after enhanced intestinal uptake of sGnRH-A and Pimozide. Journal of Fish Biology, 56, 1398-1407. Go to original source...
    88. Rutaisire J., Booth A.J. (2004): Induced ovulation, spawning, egg incubation, and hatching of the cyprinid fish Labeo victorianus in captivity. Journal of the World Aquaculture Society, 35, 383-391. Go to original source...
    89. Schally A.V., Arimura A., Coy D.H. (1980): Recent approaches to fertility control based on derivatives of LH-RH. 257-324. In: Munson P.L., Glover J., Diczfalusy E., Olson R.E. (eds.): Vitamins and hormones: advances in research and applications. Academic Press. New York. 435 pp. Go to original source...
    90. Sealfon S.C.,Weinstein H., Millar R.P. (1997): Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor. Endocrine Reviews, 18, 180-205. Go to original source... Go to PubMed...
    91. Sherwood N.M., Harvey B. (1986): Topical absorption of gonadotropin-releasing hormone (GnRH) in goldfish. General and Comparative Endrocrinology, 61, 13-19. Go to original source... Go to PubMed...
    92. Sherwood N.M., Eiden L., Brownstein M., Spiess J., Rivier J., Vale W. (1983): Characterization of a teleost gonadotropin-releasing hormone. Proceedings of the National Academy of Sciences of the United States of America, 80, 2794-2798. Go to original source... Go to PubMed...
    93. Sokolowska-Mikolajczyk M., Mikolajczyk T. (1991): Control of reproduction in Cyprinids. Rivista Italiana di Acquacoltura, 26, 209-215.
    94. Sokolowska M., Peter R.E., Nahorniak C.S., Nahorniak C.H., Chang J.P. (1984): Induction of ovulation in goldfish, Carassius auratus, by pimozide and analogues of LH-RH. Aquaculture 36, 71-83. Go to original source...
    95. Somoza G.M., Miranda L.A., Strobl-Mazzulla P., Guilgur L.G. (2002): Gonadotropin-Releasing Hormone (GnRH): From fish to mammalian brains. Cellular and Molecular Neurobiology, 22, 589-609. Go to original source... Go to PubMed...
    96. Steven C. (2000): Studies on the GnRH-GtH system of female striped bass (Morone saxatilis): effects of GnRH agonist therapy and comparison of reproductive endocrine parameters between wild and captive fish. [M.Sc. Dissertation.] University of Maryland, College Park, USA.
    97. Steven C., Gothilf Y., Holland M.C.H., Stubblefield J., Mylonas C.C., Zohar Y. (2000): Differential expression of the three GnRH genes in wild and captive striped bass, Morone saxatilis, in response to natural nad hormonally induced maturation. p. 66. In: Norberg B., Kjesbu O.S., Taranger G.L., Andersson E., Stefansson S.O. (eds.): Reproductive Physiology of Fish. University of Bergen, Bergen, Norway. 326 pp.
    98. Steven C., Lehnen N., Kight K., Ijiri S., Klenke U., Harris W.A., Zohar Y. (2003): Molecular characterization of the GnRH system in zebrafish (Danio rerio): cloning of chicken GnRH-II, adult brain expression patterns and pituitary content of salmon GnRH and chicken GnRH-II. General and Comparative Endocrinology, 133, 27-37. Go to original source... Go to PubMed...
    99. Sudova E., Machova J., Svobodova Z., Vesely T. (2007): Negative effects of malachite green and possibilities of its replacement in the treatment of fish eggs and fish: a review. Veterinarni medicina, 52, 527-539. Go to original source...
    100. Sukumasavin N., Sakulthong S., Sangthong R. (2000): A comparison of the potency of dopamine antagonists on spawning induction in Thai carp (Puntius gonionotus Bleeker). Kasetsart Journal, 34, 240-247.
    101. Svobodova Z., Kolarova J. (2004): A review of the diseases and contaminant related mortalities of tench (Tinca tinca L.). Veterinarni Medicina, 49, 19-34. Go to original source...
    102. Szabo T., Medgyasszay C., Horvath L. (2002): Ovulation induction in nase (Chondrostoma nasus, Cyprinidae) using pituitary extract or GnRH analogue combined with domperidone. Aquaculture, 203, 389-395. Go to original source...
    103. Tello J.A., Wu S., Rivier J.E., Sherwood N.M. (2008): Four functional GnRH receptors in zebrafish: analysis of structure, signaling, synteny and phylogeny. Integrative and Comparative Biology, 48, 570-587. Go to original source... Go to PubMed...
    104. Trudeau V.L. (1997): Neuroendocrine regulation of gonadotrophin II release and gonadal growth in the goldfish, Carassius auratus. Reviews of Reproduction, 2, 55-68. Go to original source... Go to PubMed...
    105. Van der Kraak G., Chang J.P., Janz D.M. (1998): Reproduction. In: Evans D.H. (ed.): The Physiology of Fishes. CRC Press LLC, Florida, USA. 465-488 pp.
    106. Vertommen J., Kinget R. (1998): Pellets as a dosage form for drugs in aquaculture: technological aspects. Journal of Applied Ichtyology, 14, 259-264. Go to original source...
    107. Volkoff H., Peter R.E. (1999): Actions of two forms of gonadotropin releasing hormone and a GnRH antagonist on spawning behavior of the goldfish Carassius auratus. General and Comparative Endocrinology, 116, 347-355. Go to original source... Go to PubMed...
    108. von Ihering Ph.D.R. (1937): A Method for inducing fish to spawn. The Progressive Fish-Culturist, 34, 15-16. Go to original source...
    109. Weber G.M., Borski R.J., Powell J.F.F., Sherwood N.M., Grau E.G. (1995): In vivo and in vitro effects of gonadotropinreleasing hormone on prolactin in the tilapia Oreochromis mossambicus. American Zoologist, 34, 121.
    110. Weber G.M., King W., Clark R.W., Hodson R.G., Sullivan C.V. (2000): Morpho-physiological predictors of ovulatory success in captive striped bass (Morone saxatilis). Aquaculture, 188, 133-146. Go to original source...
    111. Weil C., Fostier A., Horvath L., Marlot S., Berscenyi M. (1980): Profiles of plasma gonadotropin and 17-betaestradiol in the common carp, Cyprinus-carpio L, as related to spawning induced by hypophyzation or LHRH treatment. Reproduction nutrition development, 20, 1041-1050. Go to original source... Go to PubMed...
    112. Yaron, Z. (1995): Endocrine control of gametogenesis and spawning induction in the carp. Aquaculture, 129, 49-73. Go to original source...
    113. Yaron Z., Levavi-Zermonsky B. (1986): Fluctuations in gonadotropin and ovarian steroids during the annual cycle and spawning of the common carp. Fish Physiology and Biochemistry, 2, 75-86. Go to original source... Go to PubMed...
    114. Yaron Z., Sivan B. (2006): Reproduction. 343-386. In: Evans D.H., Claibourne J.B. (eds.): The Physiology of Fishes. CRC Press, Boca Raton. 601 pp.
    115. Yaron Z., Gal G., Melamed P., Rosenfeld H., Elizur A., Levavi-Sivan B. (2003): Regulation of fish gonadotropins. International Review of Cytology, 255, 131-185. Go to original source... Go to PubMed...
    116. Yu K.L., Peter R.E. (1990): Dopaminergic regulation of brain gonadotropinreleasing hormone in male goldfish during spawning behaviour. Neuroendocrinology, 52, 276-283. Go to original source... Go to PubMed...
    117. Yu K.L., Peter R.E. (1992): Adrenergic and dopaminergic regulation of gonadotropin-releasing hormone release from goldfish preoptic-anterior hypothalamus and pituitary in vitro. General and Comparative Endocrinology, 85, 138-146. Go to original source... Go to PubMed...
    118. Yu K.L., Sherwood N.M., Peter R.E. (1988): Differential distribution of two molecular forms of gonadotropinreleasing hormone in discrete brain areas of goldfish (Carassius auratus). Peptides, 9, 625-630. Go to original source... Go to PubMed...
    119. Zohar Y. (1988): Gonadotropin releasing hormone in spawning induction in teleosts: Basic and applied considerations. 47-62. In: ZoharY., Breton B. (eds.): Reproduction in Fish: Basic and Applied Aspects in Endocrinology and Genetics. INRA Press, Paris. 236 pp.
    120. Zohar Y. (1989): Fish reproduction: Its physiology and artificial manipulation. 65-119. In: Shilo M., Sarig S. (eds.): Fish Culture in Warm Water Systems. CRC Press Inc., Florida, USA. 272 pp.
    121. Zohar Y., Mylonas C.C. (2001): Endocrine manipulations of spawning in cultured fish: from hormones to genes. Aquaculture, 197, 99-136. Go to original source...
    122. Zohar Y., Goren A., Fridkin M., Elhanati E., Koch Y. (1990): Degradation of gonadotropin-releasing hormones in the gilthead seabream Sparus aurata II. Cleavage of native salmon GnRH, mammalian LHRH and their analogs in the pituitary, kidney and liver. General and Comparative Endocrinology, 79, 306-319. Go to original source... Go to PubMed...
    123. Zohar Y., Harel M., Hassin S., Tandler A. (1995): Gilthead sea bream (Sparus aurata). 94-117. In: Bromage N.R., Roberts R.J. (eds.): Broodstock Management and Egg and Larval Quality. Blackwell, Oxford, UK. 432 pp.

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