| Title |
Tracking and LET Measurements with the MiniPIX-TimePIX Detector for 60 MeV Clinical Protons |
| Authors |
- J.S.L. Yap, C.P. Welsch
Cockcroft Institute, Warrington, Cheshire, United Kingdom
- N.J.S. Bal
NIKHEF, Amsterdam, The Netherlands
- M.D. Brooke
University of Oxford, Oxford, United Kingdom
- C. Granja, C. Oancea
ADVACAM s.r.o, Prague, Czech Republic
- A. Kacperek
The Douglas Cyclotron, The Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, United Kingdom
- C.P. Welsch, J.S.L. Yap
The University of Liverpool, Liverpool, United Kingdom
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| Abstract |
Recent advancements in accelerator technology have led the rapid emergence of particle therapy facilities worldwide, affirming the need for enhanced characterisation methods of radiation fields and radiobiological effects. The Clatterbridge Cancer Centre, UK operates a 60 MeV proton beam to treat ocular cancers and facilitates studies into proton induced radiobiological responses. Accordingly, an indicator of radiation quality is the linear energy transfer (LET), a challenging physical quantity to measure. The MiniPIX-Timepix is a miniaturised, hybrid semiconductor pixel detector with a Timepix ASIC, enabling wide-range measurements of the deposited energy, position and direction of individual charged particles. High resolution spectrometric tracking and simultaneous energy measurements of single particles enable the beam profile, time, spatial dose mapping and LET (0.1 to >100 keV/µm) to be resolved. Measurements were performed to determine the LET spectra in silicon, at different positions along the Bragg Peak (BP). We discuss the experimental setup, preliminary results and applicability of the MiniPIX for clinical environments.
|
| Funding |
EU FP7 grant agreement 215080, H2020 Marie Sklodowska-Curie grant agreement No 675265, OMA - Optimization of Medical Accelerators and the Cockcroft Institute core grant STGA00076-01. |
| Paper |
download MOPAB418.PDF [6.420 MB / 4 pages] |
| Export |
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| Conference |
IPAC2021 |
| Series |
International Particle Accelerator Conference (12th) |
| Location |
Campinas, SP, Brazil |
| Date |
24-28 May 2021 |
| Publisher |
JACoW Publishing, Geneva, Switzerland |
| Editorial Board |
Liu Lin (LNLS, Campinas, Brazil); John M. Byrd (ANL, Lemont, IL, USA); Regis Neuenschwander (LNLS, Campinas, Brazil); Renan Picoreti (LNLS, Campinas, Brazil); Volker R. W. Schaa (GSI, Darmstadt, Germany) |
| Online ISBN |
978-3-95450-214-1 |
| Online ISSN |
2673-5490 |
| Received |
18 May 2021 |
| Accepted |
23 July 2021 |
| Issue Date |
25 August 2021 |
| DOI |
doi:10.18429/JACoW-IPAC2021-MOPAB418 |
| Pages |
1260-1263 |
| Copyright |
 Published by JACoW Publishing under the terms of the Creative Commons Attribution 3.0 International license. Any further distribution of this work must maintain attribution to the author(s), the published article's title, publisher, and DOI. |
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