Skip to main content

Advertisement

SpringerLink
Log in

Electrochemical Study of Breast Cancer Cells MCF-7 and Its Application in Evaluating the Effect of Diosgenin

  • Notes
  • Published:
Analytical Sciences Aims and scope Submit manuscript

Abstract

The electrochemical behavior of breast cancer cells was studied on a graphite electrode by cyclic voltammetry (CV) and potentiometric stripping analysis (PSA). In both cases, only one oxidative peak at approximately +0.75 V was observed. The peak area in PSA was used to study the growth of the cells and the effect of diosgenin on MCF-7 cells. The results showed that diosgenin can effectively inhibit the viability and proliferation of the breast cancer cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. Matsunaga and Y. Namba, Anal. Chem., 1984, 56, 798.

    Article  CAS  Google Scholar 

  2. B. Liu, S. A. Rotenberg, and M. V. Mirkin, Anal. Chem., 2002, 74, 6340.

    Article  CAS  Google Scholar 

  3. C. D. Xiao, B. Lachance, G. Sunahara, and J. H. T. Luong, Anal. Chem., 2002, 74, 5478.

    Google Scholar 

  4. M. C. Sousa and J. P. Silva, Toxicol. in Vitro, 2001, 15, 297.

    Article  CAS  Google Scholar 

  5. P. W. Becraft, Trends Genet., 2001, 17, 60.

    Article  CAS  Google Scholar 

  6. H. Myszka, D. Bednarczyk, M. Najder, and W. Kaca, Carbohyd. Res., 2003, 338, 133.

    Article  CAS  Google Scholar 

  7. S. Moalic, B. Liagre, C. Corbiere, A. Bianchi, M. Dauca, K. Bordji, and J. L. Beneytout, FEBS Lett., 2001, 506, 225.

    Article  CAS  Google Scholar 

  8. D. Jagner and A. Graneli, Anal. Chim. Acta, 1976, 83, 19.

    Article  CAS  Google Scholar 

  9. Y. Bai, X. Y. Ruan, J. Y. Mo, and Y. Q. Xie, Anal. Chim. Acta, 1998, 373, 39.

    Article  CAS  Google Scholar 

  10. J. Wang, O. Rincon, R. Polsky, and E. Dominguez, Electrochem. Commun., 2003, 5, 83.

    Article  CAS  Google Scholar 

  11. J. Feng, G. A. Luo, H. Y. Jian, R. G. Wang, and C. C. An, Electroanalysis, 2000, 12, 513.

    Article  CAS  Google Scholar 

  12. A. Sucheta, B. A. C. Ackrell, B. Cochran, and F. A. Armstrong, Nature, 1992, 356, 361.

    Article  CAS  Google Scholar 

  13. Y. J. Liu, K. Q. Deng, J. Li, S. C. Liu, and S. Z. Yao, Biophys. Chem., 2004, 112, 69.

    Article  CAS  Google Scholar 

  14. T. Matsunaga, A. Shigematsu, and N. Nakamura, Anal. Chem., 1989, 61, 2471.

    Article  CAS  Google Scholar 

  15. P. M. Ghosh, C. R. Keese, and I. Giaever, Biophys. J., 1991, 64, 602.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China

    Jia LI, Manli Guo, Yingju Liu, Shanchao Liu & Shouzhuo Yao

  2. Institute of Life Science and Technology, Hunan University, Changsha, 410082, P. R. China

    Xuanmin Liu

Authors
  1. Jia LI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xuanmin Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Manli Guo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yingju Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shanchao Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Shouzhuo Yao
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shouzhuo Yao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

LI, J., Liu, X., Guo, M. et al. Electrochemical Study of Breast Cancer Cells MCF-7 and Its Application in Evaluating the Effect of Diosgenin. ANAL. SCI. 21, 561–564 (2005). https://doi.org/10.2116/analsci.21.561

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2116/analsci.21.561

Search

Navigation