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Development of Human Hair Reference Material Supporting the Biomonitoring of Methylmercury

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Abstract

A certified reference material, NIMD-01, was developed for the analysis of mercury speciation in human hair. We collected the hair of Vietnamese males from a barbershop in Hanoi in 2016 and prepared 1200 bottles containing 3 g of sieved and blended hair powder. The certified value was given on a dry-mass basis, with the moisture content obtained by drying at 85°C for 4 h. Certified values with the expanded uncertainties (coverage factor, k = 2) were as follows: methylmercury, 0.634 ± 0.071 mg kg−1 as mercury; total mercury, 0.794 ± 0.050 mg kg−1; copper, 12.8 ± 1.4 mg kg−1; zinc, 234 ± 29 mg kg–1; selenium, 1.52 ± 0.29 mg kg–1. An indicative arsenic concentration of 0.17 ± 0.03 mg kg–1 was measured. Extended uncertainties were estimated by sample homogeneity, long- and short-term stabilities, and a characterization from measurements made by collaborating laboratories.

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Authors and Affiliations

  1. Department of International Affairs and Research, National Institute for Minamata Disease, 4058-18 Hama, Minamata, Kumamoto, 867-0008, Japan

    Koichi Haraguchi & Akito Matsuyama

  2. Department of Environment and Public Health, National Institute for Minamata Disease, 4058-18 Hama, Minamata, Kumamoto, 867-0008, Japan

    Mineshi Sakamoto & Megumi Yamamoto

  3. Laboratory Center, Hanoi University of Public Health, 1A Duc Thang Road, Duc ThangWard, Bac Tu Liem District, Hanoi, Vietnam

    Dang T. Hung

  4. Institute of Environmental Ecology, IDEA Consultants, Inc., 1334-5 Yaizu, Shizuoka, 421-0212, Japan

    Hiromitsu Nagasaka, Keisuke Uchida & Yasunori Ito

  5. Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima, 890-0065, Japan

    Hitoshi Kodamatani

  6. Department of Environmental Sciences, Jožef Stefan Institute, Jamova Cesta 39, Ljubljana, 1000, Slovenia

    Milena Horvat

  7. Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa K1N, 6N5, Canada

    Hing M. Chan

  8. Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY, 14642, USA

    Matthew Rand

  9. Centre de Toxicologie du Quebec, Institut National de Santé Publique du Quebec, 945 Wolfe Avenue, Québec G1V, 5B3, Canada

    Ciprian M. Cirtiu

  10. Department of Preventive Medicine, College of Medicine, Dong-A University, 32 Daesingongwon-ro, Seo-gu, Busan, 49201, Korea

    Byoung-Gwon Kim

  11. Environmental Medicine, University of Southern Denmark, J.B. Winsloews Vej 17a, Odense, 5000, Denmark

    Flemming Nielsen

  12. Center for Environmental Measurement and Analysis, National Institute for Environmental Studies, 16- Onokawa, Tsukuba, Ibaraki, 305-8506, Japan

    Akane Yamakawa

  13. Lumex-Marketing, Ul. Obruchevykh, 1 lit. b, St. Petersburg, 195220, Russia

    Nikolay Mashyanov

  14. Department of Chemistry, Tshwane University of Technology, 175 Nelson Manela Drive, Pretoria, 0001, South Africa

    Nikolai Panichev

  15. Institute of the Earth Sciences, St. Petersburg University, 7/9 Universitetskaya nab., St. Petersburg, 199034, Russia

    Elena Panova

  16. Nippon Instruments Corporation, 14-8 Akaoji, Takatsuki, Osaka, 569-1146, Japan

    Tomoaki Watanabe

  17. Milestone General K.K., 3-2-1 Sakato, Kawasaki, Kanagawa, 213-0012, Japan

    Naoki Kaneko

  18. Department of Applied Biosciences, Toyo University, 1-1-1 Izumino, Itakura, Gunma, 374-0193, Japan

    Jun Yoshinaga

  19. Balai Besar Laboratorium Kesehatan Jakarta, Jl. Percetakan Negara no.23B Johar Baru, Jakarta Pusat, DKI Jakarta, 10560, Indonesia

    Ranny F. Herwati

  20. Research and Development for Environmental Quality and Laboratory Center, MOEF, Kawasan Puspiptek Gedung 210, South Tangerang, Banten, 15314, Indonesia

    Alfrida E. Suoth

  21. International Mercury Laboratory Inc., 426-2 Fukuro, Minamata, Kumamoto 867-0034, Japan

    Hirokatsu Akagi

Authors
  1. Koichi Haraguchi
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  2. Mineshi Sakamoto
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  3. Akito Matsuyama
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  4. Megumi Yamamoto
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  5. Dang T. Hung
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  6. Hiromitsu Nagasaka
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  7. Keisuke Uchida
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  8. Yasunori Ito
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  9. Hitoshi Kodamatani
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  10. Milena Horvat
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  11. Hing M. Chan
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  12. Matthew Rand
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  13. Ciprian M. Cirtiu
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  14. Byoung-Gwon Kim
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  15. Flemming Nielsen
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  16. Akane Yamakawa
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  17. Nikolay Mashyanov
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  18. Nikolai Panichev
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  19. Elena Panova
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  20. Tomoaki Watanabe
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  21. Naoki Kaneko
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  22. Jun Yoshinaga
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  23. Ranny F. Herwati
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  24. Alfrida E. Suoth
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  25. Hirokatsu Akagi
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Corresponding author

Correspondence to Koichi Haraguchi.

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Haraguchi, K., Sakamoto, M., Matsuyama, A. et al. Development of Human Hair Reference Material Supporting the Biomonitoring of Methylmercury. ANAL. SCI. 36, 561–565 (2020). https://doi.org/10.2116/analsci.19SBP07

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  • DOI: https://doi.org/10.2116/analsci.19SBP07

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