Skip to main content
Log in

Economic Benefits of Including Environmental Issues as a Component of Comprehensive Asthma Care

A Managed Care Perspective

  • Review Article
  • Published:
Disease Management & Health Outcomes

Abstract

Asthma in the US is widespread, with incidence rates and morbidity increasing dramatically over the last 2 decades. The cost of asthma-related morbidity and mortality is large. There is substantial and convincing evidence that environmental factors are associated with asthma exacerbation, and more limited evidence that environmental factors play a role in the development of asthma. Educational interventions, which include an avoidance of ‘triggers’ or focus on reducing exposure to cigarette smoke, have been shown to be moderately effective. While various interventions have been shown to reduce environmental exposures, fewer studies have collected sufficient information on their effectiveness in reducing morbidity.

Cost-effectiveness analyses on educational interventions suggest that reductions in direct costs are most prominently seen for severe asthma, with the interpretation of study findings impaired by a lack of methodological consistency. One analysis from a study that included physical interventions found that the incremental cost-effectiveness ratio was $US9.20 per symptom-free day (95% CI -$US12.56, $US55.29), with potential cost savings for more severe asthma.

We point out that current practice in managed care organizations (MCOs), as well as in other settings, rarely conforms to the current clinical practice guidelines for asthma. Two reviews of the policies and actions of MCOs found that while some were integrating environmental controls into their asthma disease management plans, their commitment to these strategies was limited by lack of a strong evidence base.

We recommend the following: (i) continuation of educational programs; (ii) continuation and expansion of case management, including home visits; (iii) full integration of smoking cessation programs into asthma disease management; (iv) development of policies around reimbursement for durable goods; (v) participation in the setting of a policy agenda for population-based approaches to controlling key environmental factors; (vi) development of exploratory programs to address occupational asthma; (vii) integration, analysis and dissemination of environmental data collected by MCOs; and (viii) widespread MCO participation in research on environmental prevention of asthma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Table I
Table II
Table III
Table IV

Similar content being viewed by others

References

  1. Mannino DM, Homa DM, Akinbami LJ, et al. Surveillance for asthma: United States, 1980–1999. MMWR Surveill Summ 2002 Mar 29; 51(1): 1–13

    Google Scholar 

  2. Morbidity & Mortality: 2002 chart book on cardiovascular, lung, and blood diseases. National Institutes of Health, National Heart, Lung, and Blood Institute; 2002 May [online]. Available from URL: www.nhlbi.nih.gov/resources/docs/cht-book.htm [Accessed 2004 May 28]

  3. Asthma Prevalence, Health Care Use and Mortality, 2000–2001 [online]. Available from URL: www.cdc.gov/nchs/products/pubs/pubd/hestats/asthma/asthma.htm [Accessed 2004 May 28]

  4. American Medical Association. International Classification of Diseases, Ninth Revision, Clinical Modification. Chicago (IL): American Medical Association, 1995

    Google Scholar 

  5. World Health Organization, WHO Collaborating Centers for the Classification of Diseases. International Classification of Diseases, Tenth Revision, International Statistical Classification of Diseases and Related Health Problems. Geneva: World Health Organization, 1992–4

  6. CDC. Deaths: final data for 1999. Hyattsville (MD): US Department of Health and Human Services. CDC, National Center for Health Statistics, 2001. Natl Vital Stat Rep 2001; 49: 8

    Google Scholar 

  7. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet 1998; 351: 1225–32

    Article  Google Scholar 

  8. Smith DH, Malone DC, Lawson KA, et al. A national estimate of the economic costs of asthma. Am J Respir Crit Care Med 1997; 156: 787–93

    PubMed  CAS  Google Scholar 

  9. Ungar WJ, Coyte PC. Prospective study of the patient-level cost of asthma care in children. Pediatr Pulmonol 2001; 32: 101–8

    Article  PubMed  CAS  Google Scholar 

  10. Lozano P, Sullivan SD, Smith DH, et al. The economic burden of asthma in US children: estimates from the national Medical Expenditure Survey. J Allergy Clin Immunol 1999; 104: 957–63

    Article  PubMed  CAS  Google Scholar 

  11. Mushinski M. Average hospital charges for asthma treatment: United States, 1995. Stat Bull Metrop Insur Co 1997; 78: 26–32

    PubMed  CAS  Google Scholar 

  12. Stanford R, McLaughlin T, Okamoto LJ. The cost of asthma in the emergency department and hospital. Am J Respir Crit Care Med 1999; 160: 211–5

    PubMed  CAS  Google Scholar 

  13. Meurer JR, Kuhn M, Varghese G, et al. Charges for childhood asthma by hospital characteristics. Pediatrics 1998; 102(6): e70

    Article  PubMed  CAS  Google Scholar 

  14. Weiss KB, Gergen PJ, Hodgson TA. An economic evaluation of asthma in the US. N Engl J Med 1992; 236: 862–6

    Article  Google Scholar 

  15. Weiss KB, Sullivan SD. The health economics of asthma and rhinitis: I. Assessing the economic impact. J Allergy Clin Immunol 2001; 107: 3–8

    Article  PubMed  CAS  Google Scholar 

  16. Medical Economics Company, Inc. Drug topics red book. Cardinal V, ed. Montvale (NJ): Medical Economics Company, Inc., 2003

    Google Scholar 

  17. Sheth K, Borker R, Emmett A, et al. Cost-effectiveness comparison of salmeterol/fluticasone Propionate vs montelukast in the treatment of adults with persistent asthma. Pharmacoeconomics 2002; 20: 909–18

    Article  PubMed  Google Scholar 

  18. Paltiel AD, Fuhlbrigge AL, Kitch BT, et al. Cost-effectiveness of inhaled corticosteroids in adults with mild-to-moderate asthma: results from the asthma policy model. J Allergy Clin Immunol 2001; 108: 39–49

    Article  PubMed  CAS  Google Scholar 

  19. Pathak DS, Davis EA, Stanford RH. Economic impact of asthma therapy with fluticasone Propionate, montelukast or zafirlukast in a managed care population. Pharmacotherapy 2002; 22: 131–3

    Article  Google Scholar 

  20. Etzel RA. How environmental exposures influence the development and exacerbation of asthma. Pediatrics 2003; 112: 233–9

    PubMed  Google Scholar 

  21. Neas LM, Dockery DW, Burge H, et al. Fungus spores, air pollutants, and other determinants of peak expiratory flow rate in children. Am J Epidemiol 1996; 143(8): 797–807

    Article  PubMed  CAS  Google Scholar 

  22. Schwartz J. Air pollution and hospital admissions for respiratory disease. Epidemiology 1996; 7(1): 20–8

    Article  PubMed  CAS  Google Scholar 

  23. English P, Neutra R, Scalf R, et al. Examining associations between childhood asthma and traffic flow using a geographic information system. Environ Health Perspect 1999; 107: 761–7

    Article  PubMed  CAS  Google Scholar 

  24. Koenig JQ. Air pollution and asthma. J Allergy Clin Immunol 1999; 104: 717–22

    Article  PubMed  CAS  Google Scholar 

  25. US Centers for Disease Control and Prevention. Surveillance for asthma: United States, 1960–1995. MMWR Morb Mortal Wkly Rep 1998; 47(SS-1): 1–28

    Google Scholar 

  26. Raizenne M, Dales R, Burnett R. Air pollution exposures and children’s health. Can J Public Health 1998; 89: S43–8

    PubMed  Google Scholar 

  27. US Environmental Protection Agency. Latest findings on national air quality: 1999 status and trends. Triangle Park (NC): US EPA. 2000 Aug (EPA-454/F-00-002)

    Google Scholar 

  28. Institute of Medicine. Clearing the air: asthma and indoor exposures. Committee on the Assessment of Asthma and Indoor Air, Division of Health Promotion and Disease Prevention, Institute of Medicine. Washington, DC: The National Academies Press, 2000

    Google Scholar 

  29. Ng TP, Seet CS, Tan WC, et al. Nitrogen dioxide exposure from domestic gas cooking and airway response in asthmatic women. Thorax 2001; 56: 596–601

    Article  PubMed  CAS  Google Scholar 

  30. Hendry KM, Cole EC. A review of mycotoxins in indoor air. J Toxicol Environ Health 1993; 38: 183–98

    Article  PubMed  CAS  Google Scholar 

  31. Shen H-D, Tam MF, Chou H, et al. The importance of serine proteinases as aeroallergens associated with asthma. Int Arch Allergy Immunol 1999; 119: 259–64

    Article  PubMed  CAS  Google Scholar 

  32. Rosenstreich DL, Eggleston P, Kattan M, et al. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N Engl J Med 1997; 336(19): 1356–63

    Article  PubMed  CAS  Google Scholar 

  33. Guerin MR, Jenkins RA, Tomkins BA. The chemistry of environmental tobacco smoke: composition and measurement. Boca Raton (FL): Lewis Publishers, 1992

    Google Scholar 

  34. National Research Council. Environmental tobacco smoke: measuring exposures and assessing health effects. Washington, DC: National Academy Press, 1986

    Google Scholar 

  35. US Environmental Protection Agency. Respiratory health effects of passive smoking: lung cancer and other disorders. Washington, DC: United States Environmental Protection Agency, Office of Research and Development, 1992

    Google Scholar 

  36. California Environmental Protection Agency. Health effects of exposure to environmental tobacco smoke: final report. Berkeley (CA): California Environmental Protection Agency, Office of Health Hazard Assessment, 1997

    Google Scholar 

  37. Greenberg SB. Respiratory consequences of rhinovirus infection. Arch Intern Med 2003; 163: 278–84

    Article  PubMed  Google Scholar 

  38. McCutcheon H, Fitzgerald M. The public health problem of acute respiratory illness in childcare. J Clin Nurs 2001; 10(3): 305–10

    Article  PubMed  CAS  Google Scholar 

  39. von Mutius E. Environmental factors influencing the development and progression of pediatric asthma. J Allergy Clin Immunol 2002; 109: S525–32

    Article  Google Scholar 

  40. Boden L. Workers’ compensation. In: BS Levy, DH Wegman, editors. Occupational health: recognizing and preventing work-related disease and injury. 4th ed. Boston (MA): Lippincott, Williams & Wilkens, 2000: 237–56

    Google Scholar 

  41. Bardana Jr EJ. Occupational asthma and allergies. J Allergy Clin Immunol 2003; 111: S530–9

    Article  PubMed  CAS  Google Scholar 

  42. Wolf FM, Guevara JP, Gram CM, et al. Educational interventions for asthma in children. Available in The Cochrane Library [database on disk and CD-ROM]. Updated quarterly. The Cochrane Collaboration; issue 1. Oxford: Update Software, 2003

    Google Scholar 

  43. Lumley J, Oliver S, Waters E. Interventions for promoting smoking cessation during pregnancy. Available in The Cochrane Library [database on disk and CD-ROM]. Updated quarterly. The Cochrane Collaboration; issue 1. Oxford: Update Software, 2003

    Google Scholar 

  44. Karnath B. Smoking cessation. Am J Med 2002; 112: 399–405

    Article  PubMed  Google Scholar 

  45. Hovell MF, Zakarian JM, Wahlgren DR, et al. Reducing children’s exposure to environmental tobacco smoke: the empirical evidence and directions for future research. Tob Control 2000; 9 Suppl. 2: II40–7

    PubMed  Google Scholar 

  46. Wakefield M, Banham D, McCaul K, et al. Effects of feedback regarding urinary cotinine and brief tailored advice on home smoking restrictions among lowincome parents of children with asthma: a controlled trial. Prev Med 2002; 34: 58–65

    Article  PubMed  Google Scholar 

  47. Wilson SR, Yamada EG, Sudharkar R, et al. A controlled trial of an environmental tobacco smoke reduction intervention in low-income children with asthma. Chest 2001; 120: 1709–22

    Article  PubMed  CAS  Google Scholar 

  48. Gotzsche PC, Johansen HK, Burr ML, et al. House dust mite control measures for asthma. Available in The Cochrane Library [database on disk and CD-ROM]. Updated quarterly. The Cochrane Collaboration; issue 1. Oxford: Update Software 2003

    Google Scholar 

  49. McDonald E, Cook D, Newman T, et al. Effect of air filtration systems on asthma: a systematic review of randomized trials. Chest 2002; 122: 1535–42

    Article  PubMed  Google Scholar 

  50. Woodcock A, Forster L, Matthews E, et al. Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma. N Engl J Med 2003; 349: 225–36

    Article  PubMed  Google Scholar 

  51. Custovic A, Simpson BM, Simpson A, et al. Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during the first year of life: a randomized trial. Lancet 2001; 358: 188–93

    Article  PubMed  CAS  Google Scholar 

  52. Evans R, Gergen PJ, Herman M, et al. A randomized clinical trial to reduce asthma morbidity among inner-city children: results of the National Cooperative Inner-City Asthma Study. Pediatrics 1999; 135: 332–8

    Article  Google Scholar 

  53. Popplewell EJ, Innes VA, Lloyd-Hughes S, et al. The effect of high-efficiency and standard vacuum-cleaners on mite, cat and dog allergen levels and clinical progress. Pediatr Allergy Immunol 2000; 11(3): 142–8

    Article  PubMed  CAS  Google Scholar 

  54. Carter M, Perzanowski MS, Raymond A, et al. Home interventions in the treatment of asthma among inner-city children. J Allergy Clin Immunol 2001; 108: 732–7

    Article  PubMed  CAS  Google Scholar 

  55. Francis H, Fletcher G, Anthony C, et al. Clinical effects of air filters in homes of asthmatic adults sensitized and exposed to pet allergens. Clin Exp Allergy 2003; 33: 101–5

    Article  PubMed  CAS  Google Scholar 

  56. Thomson H, Petticrew M, Douglas M. “Health impact assessment of housing improvements: incorporating research evidence.” J Epidemiol Community Health 2003; 57: 11–6

    Article  PubMed  CAS  Google Scholar 

  57. Russell LB, Siegel JE, Daniels N, et al. Cost-effectiveness analysis as a guide to resource allocation in health: roles and limitations. In: Gold MR, Siegel JE, Russell LB, et al., editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1996: 3–24

    Google Scholar 

  58. Gold MR, Siegel JE, Russell LB, et al., editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1996

    Google Scholar 

  59. Torrance GW, Siegel JE, Luce BR. Framing and designing the cost-effectiveness analysis. In: Gold MR, Siegel JE, Russell LB, et al., editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1996: 54–81

    Google Scholar 

  60. Sullivan SD, Weiss KB, Lynn H, et al. The cost-effectiveness of an inner-city asthma intervention for children. J Allergy Clin Immunol 2002; 110: 576–81

    Article  PubMed  Google Scholar 

  61. Krieger JK, Takaro TK, Allen C, et al. The Seattle-King County healthy homes project: implementation of a comprehensive approach to improving indoor environmental quality for low-income children with asthma. Environ Health Perspect 2002; 110 Suppl. 2: 311–22

    PubMed  Google Scholar 

  62. Clark NM, Feldman CH, Evans D, et al. The impact of health education on frequency and cost of health care use by low income children with asthma. J Allergy Clin Immunol 1986; 78: 108–15

    Article  PubMed  CAS  Google Scholar 

  63. Weinstein AG, McKee L, Stapleford J, et al. An economic evaluation of short term inpatient rehabilitation for children with severe asthma. J Allergy Clin Immunol 1996; 98: 264–73

    Article  PubMed  CAS  Google Scholar 

  64. Ronchetti R, Indinnimeo L, Bonci E, et al. Asthma self-management programmes in a population of Italian children: a multicentric study. Italian Study Group on Asthma Self-Management Programmes. Eur Respir J 1997; 10: 1248–53

    Article  PubMed  CAS  Google Scholar 

  65. Liljas B, Lahdensuo A. Is asthma self-management cost-effective? Patient Educ Couns 1997; 32: S97–S104

    Article  PubMed  CAS  Google Scholar 

  66. Delate T, Motheral B. Conclusions of cost-effectiveness for an asthma intervention might not be warranted. J Allergy Clin Immunol 2003; 111: 654–5

    Article  PubMed  Google Scholar 

  67. Feenstra TL, Rutten-van Molken MPMH, Jager JC, et al. Cost effectiveness of guideline advice for children with asthma: a literature review. Pediatr Pulmonol 2002; 34: 442–54

    Article  PubMed  Google Scholar 

  68. Managed Care Fact Sheets. Managed Care National Statistics [online]. Available from URL: http://www.mcareol.com/factshts/factnati.htm [Accessed 2003 Jun 6]

  69. Lozano P, Lieu T. Asthma in managed care. Pediatr Ann 1999; 28(1): 74–80

    PubMed  CAS  Google Scholar 

  70. Mills DM, Argus J, Chestnut LG, et al. Asthma management programs: are they cost effective? Washington, DC: US Environmental Protection Agency, 2000

    Google Scholar 

  71. National Guideline Clearinghouse (NGC). Available from URL: http://www.guideline.gov/ [Accessed 2003 Jun 25]

  72. Brugge D, Carranza L, Steinbach S, et al. Environmental management of asthma at Massachusetts managed care organizations. J Public Health Manag Pract 2001; 7(5): 36–5

    PubMed  CAS  Google Scholar 

  73. Brugge D, Bagley J, Hyde J. Environmental management of asthma at top-ranked US managed care organizations. J Asthma. 2003; 40: 605–14

    Article  PubMed  Google Scholar 

  74. Warman KI, Jacobs A, Silver E. If we prescribe it, will they come?: access to asthma equipment for Medicaid-insured children and adults in the Bronx, NY. Arch Pediatr Adolesc Med 2002; 156(7): 673–7

    PubMed  Google Scholar 

  75. Diette G, Skinner E, Markson L, et al. Consistency of care with national guidelines for children with asthma in managed care. J Pediatr 2001, 64

  76. Donahue J, Fuhlbrigge A, Finkelstein J, et al. The pediatric asthma care patient outcomes research team, asthma pharmacotherapy and utilization by children in 3 managed care organizations. J Allergy Clin Immunol 2000; 106(6): 1108–14

    Article  PubMed  CAS  Google Scholar 

  77. Sheilds S, Finkelstein J, Comstock C, et al. Process of care for Medicaid-enrolled children with asthma: served by community health centers and other providers. Med Care 2002; 40(4): 303–14

    Article  Google Scholar 

  78. Piercoro L, Potoski M, Talbert J, et al. Asthma prevalence, cost and adherence with expert guidelines on the utilization of health care services and costs in a state Medicaid population. Health Serv Res 2001; 36(2): 357–71

    Google Scholar 

  79. Merrick N, Houchens R, Tillisch S, et al. Quality of hospital care of children with asthma: Medicaid versus privately insured patients. J Health Care Poor Under-served 2001; 12(2): 192–207

    Article  CAS  Google Scholar 

  80. Apter A, VanHoof T, Sherwin T, et al. Assessing the quality of asthma care provided to Medicaid patients enrolled in managed care organizations in Connecticut. Ann Allergy Asthma Immunol 2001; (86) 2: 211–8

    Article  PubMed  CAS  Google Scholar 

  81. Vinicor F. Diabetes mellitus and asthma: twin challenges for public health and managed care systems. Am J Prev Med 1998; 14(3 Suppl.): 87–92

    Article  PubMed  CAS  Google Scholar 

  82. Kinney PL, Northridge ME, Chew GL, et al. On the front lines: an environmental asthma intervention in New York City. Am J Public Health 2002; 92: 24–6

    Article  PubMed  Google Scholar 

  83. Brugge D, Vallarino J, Ascolillo L, et al. Comparison of multiple environmental factors for asthmatic children in public housing. Indoor Air 2003; 13: 18–27

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

The authors thank Barbara Gill for her assistance in preparing the manuscript. Authors Drs Brugge, Levy, and Steinbach are members of the Healthy Public Housing Initiative (HPHI), which is funded by the U.S. Department of Housing and Urban Development, W.K. Kellogg Foundation, Jessie B. Cox Family Trust and The Boston Foundation. The authors declare that they have no conflict of interest directly relevant to this review.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Doug Brugge.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Brugge, D., Hyde, J., Weinbach, B.H. et al. Economic Benefits of Including Environmental Issues as a Component of Comprehensive Asthma Care. Dis-Manage-Health-Outcomes 12, 259–272 (2004). https://doi.org/10.2165/00115677-200412040-00006

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00115677-200412040-00006

Keywords

Navigation