Corpus callosum in aging and neurodegenerative diseases

Papers of special note have been highlighted as: ▪ of interest ▪▪ of considerable interest

References

• 1  Tomasch J. Size, distribution, and number of fibers in the human corpus callosum. Anat. Rec.119,119–135 (1954).
  Medline CASGoogle Scholar
• 2  Di Paola M, Di Iulio F, Cherubini A et al. When, where, and how the corpus callosum changes in MCI and AD: a multimodal MRI study. Neurology74(14),1136–1142 (2010).▪ Large review of results from MRI studies on the corpus callosum (CC) in patients with Alzheimer’s disease.
  Medline CASGoogle Scholar
• 3  Teipel S, Bayer W, Alexander G et al. Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer’s disease in relation to dementia severity: evidence for early neocortical degeneration. Neurobiol. Aging24(1),85–94 (2003).
  Medline CASGoogle Scholar
• 4  Frederiksen KS, Garde E, Skimminge A et al. Corpus callosum tissue loss and development of motor and global cognitive impairment: the LADIS study. Dement. Geriatr. Cogn. Disord.32(4),279–286 (2011).
  MedlineGoogle Scholar
• 5  Yamauchi H, Fukuyama H, Nagahama Y et al. Comparison of the pattern of atrophy of the corpus callosum in frontotemporal dementia, progressive supranuclear palsy, and Alzheimer’s disease. J. Neurol. Neurosurg. Psychiatry69(1),623–629 (2000).
  Medline CASGoogle Scholar
• 6  Di Paola M, Luders E, Cherubini A et al. Multimodal MRI analysis of the corpus callosum reveals white matter differences in presymptomatic and early Huntington’s disease. Cereb. Cortex doi:10.1093/cercor/bhr360 (2012) (Epub ahead of print).
  MedlineGoogle Scholar
• 7  Mitelman SA, Nikiforova YK, Canfield EL et al. A longitudinal study of the corpus callosum in chronic schizophrenia. Schizophr. Res.114(1–3),144–153 (2009).
  MedlineGoogle Scholar
• 8  Bloom JS, Hynd GW. The role of the corpus callosum in interhemispheric transfer of information: excitation or inhibition? Neuropsychol. Rev.15(2),59–71 (2005).▪ Excitatory and inhibitory models of the CC.
  MedlineGoogle Scholar
• 9  Gazzaniga MS. Cerebral specialization and interhemispheric communication: does the corpus callosum enable the human condition? Brain123,1293–1326 (2000).▪ Review of the research in split-brain patients by one of the pioneers within the field.
  MedlineGoogle Scholar
• 10  Voneida TJ. Roger Wolcott Sperry, 20 August 1913–1917 April 1994. Biogr. Mem. Fellows R. Soc.43,461–470 (1997).
  Medline CASGoogle Scholar
• 11  Fame RM, Macdonald JL, Macklis JD. Development, specification, and diversity of callosal projection neurons. Trends Neurosci.34(1),41–50 (2011).
  Medline CASGoogle Scholar
• 12  Aboitiz F, Scheibel AB, Fisher RS, Zaidel E. Fiber composition of the human corpus callosum. Science598(1–2),143–153 (1992).▪▪ Often-cited work on the fiber composition of the human CC.
  CASGoogle Scholar
• 13  Aboitiz F, Scheibel AB, Fisher S, Zaidel E. Individual differences in brain asymmetries and fiber composition in the human corpus callosum. Brain598(1–2),154–161 (1992).
  CASGoogle Scholar
• 14  Tate DF, Sampat M, Harezlak J et al. Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. J. Neurovirol.17(4),368–379 (2011).
  MedlineGoogle Scholar
• 15  Hallam BJ, Brown WS, Ross C et al. Regional atrophy of the corpus callosum in dementia. J. Int. Neuropsychol. Soc.14(3),414–423 (2008).
  MedlineGoogle Scholar
• 16  Thomann P, Wustenberg T, Pantel J, Essig M, Schroder J. Structural changes of the corpus callosum in mild cognitive impairment and Alzheimer’s disease. Dement. Geriatr. Cogn. Disord.21(4),215–220 (2006).
  MedlineGoogle Scholar
• 17  Chaim TM, Duran FLS, Uchida RR, Périco CM, de Castro CC, Busatto GF. Volumetric reduction of the corpus callosum in Alzheimer’s disease in vivo as assessed with voxel-based morphometry. Psychiatry Res.154(1),59–68 (2007).
  MedlineGoogle Scholar
• 18  Di Paola M, Luders E, Di Iulio F et al. Callosal atrophy in mild cognitive impairment and Alzheimer’s disease: different effects in different stages. Neuroimage49(1),141–149 (2010).
  MedlineGoogle Scholar
• 19  Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum: a postmortem morphological study. Brain112(Pt 3),799–835 (1989).
  MedlineGoogle Scholar
• 20  Ryberg C, Rostrup E, Stegmann MB et al. Clinical significance of corpus callosum atrophy in a mixed elderly population. Neurobiol. Aging28(6),955–963 (2007).
  Medline CASGoogle Scholar
• 21  Wilson CJ. Morphology and synaptic connections of crossed corticostriatal neurons in the rat. J. Comp. Neurol.263(4),567–580 (1987).
  Medline CASGoogle Scholar
• 22  Jarbo K, Verstynen T, Schneider W. In vivo quantification of global connectivity in the human corpus callosum. Neuroimage59(3),1988–1996 (2012).
  MedlineGoogle Scholar
• 23  Huang H, Zhang J, Jiang H et al. DTI tractography based parcellation of white matter: application to the mid-sagittal morphology of corpus callosum. Neuroimage26(1),195–205 (2005).
  MedlineGoogle Scholar
• 24  Cook ND. Homotopic callosal inhibition. Brain Lang.23(2),116–125 (1984).
  Medline CASGoogle Scholar
• 25  Westerhausen R, Kreuder F, Woerner W et al. Interhemispheric transfer time and structural properties of the corpus callosum. Neurosci. Lett.409(2),140–145 (2006).
  Medline CASGoogle Scholar
• 26  Voineskos AN, Farzan F, Barr MS et al. The role of the corpus callosum in transcranial magnetic stimulation induced interhemispheric signal propagation. Biol. Psychiatry68(9),825–831 (2010).
  MedlineGoogle Scholar
• 27  Stephan KE, Penny WD, Marshall JC, Fink GR, Friston KJ. Investigating the functional role of callosal connections with dynamic causal models. Ann. NY Acad. Sci.1064,16–36 (2005).
  MedlineGoogle Scholar
• 28  Nowicka A, Tacikowski P. Transcallosal transfer of information and functional asymmetry of the human brain. Laterality16(1),35–74 (2011).▪▪ Research on laterality in humans with emphasis on the role of the CC.
  MedlineGoogle Scholar
• 29  Park H-J, Kim JJ, Lee S-K et al. Corpus callosal connection mapping using cortical gray matter parcellation and DT-MRI. Hum. Brain Mapp.29(5),503–516 (2008).▪ Extremely detailed map of cortical projections to the CC based on diffusion-weighted MRI.
  MedlineGoogle Scholar
• 30  Zarei M, Johansen-Berg H, Smith S, Ciccarelli O, Thompson AJ, Matthews PM. Functional anatomy of interhemispheric cortical connections in the human brain. J. Anat.209(3),311–320 (2006).
  MedlineGoogle Scholar
• 31  Le Bihan D, Mangin JF, Poupon C et al. Diffusion tensor imaging: concepts and applications. J. Magn. Reson. Imaging13(4),534–546 (2001).
  Medline CASGoogle Scholar
• 32  Chao YP, Cho KH, Yeh CH, Chou KH, Chen JH, Lin CP. Probabilistic topography of human corpus callosum using cytoarchitectural parcellation and high angular resolution diffusion imaging tractography. Hum. Brain Mapp.30(10),3172–3187 (2009).
  MedlineGoogle Scholar
• 33  Hofer S, Frahm J. Topography of the human corpus callosum revisited – comprehensive fiber tractography using diffusion tensor magnetic resonance imaging. Neuroimage32(3),989–994 (2006).
  MedlineGoogle Scholar
• 34  Shah A, Jhawar SS, Goel A. Analysis of the anatomy of the Papez circuit and adjoining limbic system by fiber dissection techniques. J. Clin. Neurosci.19(2),289–298 (2012).
  MedlineGoogle Scholar
• 35  Ellenberg L, Sperry R. Capacity for holding sustained attention following commissurotomy. Cortex15,421–438 (1979).
  Medline CASGoogle Scholar
• 36  Dimond S. Depletion of attentional capacity after total commissurotomy in man. Brain99,347–356 (1976).
  Medline CASGoogle Scholar
• 37  David AS, Wacharasindhu A, Lishman WA. Severe psychiatric disturbance and abnormalities of the corpus callosum: review and case series. J. Neurol. Neurosurg. Psychiatry56,85–93 (1993).
  Medline CASGoogle Scholar
• 38  Zaidel D, Sperry R. Memory impairment after commissurotomy in man. Brain97,253–272 (1974).
  Google Scholar
• 39  Devinsky O. Callosal lesions and behavior: history and modern concepts. Epilepsy Behav.4(6),607–617 (2003).
  MedlineGoogle Scholar
• 40  Damasio A, Damasio H. Hemianopia, hemiachromatopsia and the mechanisms of alexia. Cortex22,161–169 (1986).
  Medline CASGoogle Scholar
• 41  Aralasmak A, Ulmer JL, Kocak M, Salvan CV, Hillis AE, Yousem DM. Association, commissural, and projection pathways and their functional deficit reported in literature. J. Comp. Assist. Tomog.30(5),695–715 (2006).
  MedlineGoogle Scholar
• 42  Paul LK, Brown WS, Adolphs R et al. Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat. Rev. Neurosci.8(4),287–299 (2007).
  Medline CASGoogle Scholar
• 43  Schulte T, Sullivan EV, Müller-Oehring EM, Adalsteinsson E, Pfefferbaum A. Corpus callosal microstructural integrity influences interhemispheric processing: a diffusion tensor imaging study. Cereb. Cortex15(9),1384–1392 (2005).
  Medline CASGoogle Scholar
• 44  Pogarell O, Teipel SJ, Juckel G et al. EEG coherence reflects regional corpus callosum area in Alzheimer’s disease. J. Neurol. Neurosurg. Psychiatry76(1),109–111 (2005).
  Medline CASGoogle Scholar
• 45  Nowicka A, Grabowska A, Fersten E. Interhemispheric transmission of information and functional asymmetry of the human brain. Neuropsychologia34(2),147–151 (1996).
  Medline CASGoogle Scholar
• 46  Delbeuck X, Collette F, Van der Linden M. Is Alzheimer’s disease a disconnection syndrome? Evidence from a crossmodal audio-visual illusory experiment. Neuropsychologia45(14),3315–3323 (2007).
  Medline CASGoogle Scholar
• 47  Catani M, Mesulam M. What is a disconnection syndrome? Cortex44(8),911–913 (2008).
  MedlineGoogle Scholar
• 48  Ota M, Obata T, Akine Y et al. Age-related degeneration of corpus callosum measured with diffusion tensor imaging. Neuroimage31(4),1445–1452 (2006).
  MedlineGoogle Scholar
• 49  McLaughlin NC, Paul RH, Grieve SM et al. Diffusion tensor imaging of the corpus callosum: a cross-sectional study across the lifespan. Int. J. Dev. Neurosci.25(4),215–221 (2007).
  MedlineGoogle Scholar
• 50  Michielse S, Coupland N, Camicioli R et al. Selective effects of aging on brain white matter microstructure: a diffusion tensor imaging tractography study. Neuroimage52(4),1190–1201 (2010).
  MedlineGoogle Scholar
• 51  Davis S, Dennis N, Buchler NG, White LE, Madden DJ, Cabeza R. Assessing the effects of age on long white matter tracts using diffusion tensor tractography. Neuroimage46(2),530–541 (2009).
  MedlineGoogle Scholar
• 52  Sullivan EV, Rohlfing T, Pfefferbaum A. Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance. Neurobiol. Aging31(3),464–481 (2010).
  MedlineGoogle Scholar
• 53  Bartzokis G, Sultzer D, Lu PH, Nuechterlein KH, Mintz J, Cummings JL. Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical ‘disconnection’ in aging and Alzheimer’s disease. Neurobiol. Aging25(7),843–851 (2004).
  Medline CASGoogle Scholar
• 54  Aboitiz F, Scheibel ZE. Morphometry of the Sylvian fissure and the corpus callosum, with emphasis on sex differences. Brain115(Pt 5),1521–1541 (1992).
  MedlineGoogle Scholar
• 55  Jokinen H, Ryberg C, Kalska H et al. Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study. J. Neurol. Neurosurg. Psychiatry78(5),491–496 (2007).
  MedlineGoogle Scholar
• 56  Jokinen H, Frederiksen KS, Garde E et al. Callosal tissue loss parallels subtle decline in psychomotor speed. A longitudinal quantitative MRI study. The LADIS Study. Neuropsychologia50(7),1650–1655 (2012).
  MedlineGoogle Scholar
• 57  Zahr NM, Rohlfing T, Pfefferbaum A, Sullivan EV. Problem solving, working memory, and motor correlates of association and commissural fiber bundles in normal aging: a quantitative fiber tracking study. Neuroimage44(3),1050–1062 (2009).
  MedlineGoogle Scholar
• 58  Kennedy KM, Raz N. Aging white matter and cognition: differential effects of regional variations in diffusion properties on memory, executive functions, and speed. Neuropsychologia47(3),916–927 (2009).
  MedlineGoogle Scholar
• 59  Fling BW, Chapekis M, Reuter-lorenz PA et al. Age differences in callosal contributions to cognitive processes. Neuropsychologia49(9),2564–2569 (2011).
  MedlineGoogle Scholar
• 60  West RL. An application of prefrontal cortex function theory to cognitive aging. Psychol. Bull.120(Pt 5),272–292 (1996).
  Medline CASGoogle Scholar
• 61  Tisserand D, Jolles J. On the involvement of prefrontal networks in cognitive ageing. Cortex39(4–5),1107–1128 (2003).
  MedlineGoogle Scholar
• 62  Lu P, Lee G, Raven E et al. Age-related slowing in cognitive processing speed is associated with myelin integrity in a very healthy elderly sample. J. Clin. Exp. Neuropsychol.33(10),1059–1068 (2011).
  MedlineGoogle Scholar
• 63  Ryberg C, Rostrup E, Sjöstrand K et al. White matter changes contribute to corpus callosum atrophy in the elderly: the LADIS study. Am. J. Neuroradiol.29(8),1498–1504 (2008).
  Medline CASGoogle Scholar
• 64  Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5 T in Alzheimer’s dementia and normal aging deficiency. Am. J. Roentgen.149(2),351–356 (1987).
  Medline CASGoogle Scholar
• 65  Awad IA, Spetzler RF, Hodak JA et al. Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. 1. Correlation with age and cerebrovascular risk factors. Stroke17,1084–1089 (1986).
  Medline CASGoogle Scholar
• 66  Goldstein LB, Adams R, Alberts MJ et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Stroke37,1583–1633 (2006).
  MedlineGoogle Scholar
• 67  van Swieten JC, van den Hout JH, van Ketel BA et al. Periventricular lesions in the white matter on magnetic resonance imaging in the elderly: a morphometric correlation with arteriolosclerosis and dilated perivascular spaces. Brain114(Pt 2),761–774 (1991).
  MedlineGoogle Scholar
• 68  Pantoni L, Garcia JH. The significance of cerebral white matter abnormalities 100 years after Binswanger’s report: a review. Stroke26,1293–1301 (1995).
  Medline CASGoogle Scholar
• 69  Meguro K, Constans JM, Courtheoux P, Theron J, Viader F, Yamadori A. Atrophy of the corpus callosum correlates with white matter lesions in patients with cerebral ischaemia. Neuroradiology42,413–419 (2000).
  Medline CASGoogle Scholar
• 70  Griebe M, Förster A, Wessa M et al. Loss of callosal fibre integrity in healthy elderly with age-related white matter changes. J. Neurol.258(8),1451–1459 (2011).
  MedlineGoogle Scholar
• 71  Frederiksen KS, Garde E, Skimminge A et al. Corpus callosum atrophy in patients with mild Alzheimer’s disease. Neurodegener. Dis.8(6),476–482 (2011).
  MedlineGoogle Scholar
• 72  Teipel SJ, Bayer W, Alexander GE et al. Progression of corpus callosum atrophy in Alzheimer disease. Arch. Neurol.59(2),243–248 (2002).
  MedlineGoogle Scholar
• 73  Teipel SJ, Hampel H, Alexander GE et al. Dissociation between corpus callosum atrophy and white matter pathology in Alzheimer’ s disease. Neurology51(5),1381–1385 (1998).
  Medline CASGoogle Scholar
• 74  Hampel H, Teipel SJ, Alexander GE et al. Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Arch. Neurol.55(2),193–198 (1998).
  Medline CASGoogle Scholar
• 75  Yamauchi H, Fukuyama H, Shio H. Corpus callosum atrophy in patients with leukoaraiosis may indicate global cognitive impairment. Stroke31,1515–1520 (2000).
  Medline CASGoogle Scholar
• 76  Cabeza R, Anderson ND, Locantore JK, McIntosh AR. Aging gracefully: compensatory brain activity in high-performing older adults. Neuroimage17(3),1394–1402 (2002).
  MedlineGoogle Scholar
• 77  Cabeza R. Hemispheric asymmetry reduction in older adults: the HAROLD model. Psychol. Aging17(1),85–100 (2002).
  MedlineGoogle Scholar
• 78  Davis S, Kragel JE, Madden D, Cabeza R. The architecture of cross-hemispheric communication in the aging brain: linking behavior to functional and structural connectivity. Cereb. Cortex22(1),232–242 (2012).
  MedlineGoogle Scholar
• 79  Persson J, Nyberg L, Lind J et al. Structure-function correlates of cognitive decline in aging. Cereb. Cortex16,907–915 (2006).
  MedlineGoogle Scholar
• 80  Dolcos F, Rice HJ, Cabeza R. Hemispheric asymmetry and aging: right hemisphere decline or asymmetry reduction. Neurosci. Biobehav. Rev.26(7),819–825 (2002).
  MedlineGoogle Scholar
• 81  Wang PJ, Saykin AJ, Flashman L et al. Regionally specific atrophy of the corpus callosum in AD, MCI and cognitive complaints. Neurobiol. Aging27(11),1613–1617 (2006).
  MedlineGoogle Scholar
• 82  Lyoo IK, Satlin A, Lee CK, Renshaw PF. Regional atrophy of the corpus callosum in subjects with Alzheimer’s disease and multi-infarct dementia. Psychiatry Res.16(74),63–72 (1997).
  Google Scholar
• 83  Hensel A, Wolf H, Kruggel F et al. Morphometry of the corpus callosum in patients with questionable and mild dementia. J. Neurol. Neurosurg. Psychiatry73(1),59–61 (2002).
  Medline CASGoogle Scholar
• 84  Zarei M, Damoiseaux JS, Morgese C et al. Regional white matter integrity differentiates between vascular dementia and Alzheimer disease. Stroke40(3),773–779 (2009).
  MedlineGoogle Scholar
• 85  Chen TF, Lin CC, Chen YF et al. Diffusion tensor changes in patients with amnesic mild cognitive impairment and various dementias. Psychiatry Res.173(1),15–21 (2009).
  MedlineGoogle Scholar
• 86  Stahl R, Dietrich O, Teipel SJ, Hampel H, Reiser MF, Schoenberg SO. White matter damage in Alzheimer disease and mild cognitive impairment: assessment with diffusion-tensor MR imaging and parallel imaging techniques. Radiology243(2),483–492 (2007).
  MedlineGoogle Scholar
• 87  Ukmar M, Makuc E, Onor ML, Garbin G, Trevisiol M, Cova MA. Evaluation of white matter damage in patients with Alzheimer’s disease and in patients with mild cognitive impairment by using diffusion tensor imaging. Radiol. Med.113(6),915–922 (2008).
  Medline CASGoogle Scholar
• 88  Wang L, Goldstein FC, Veledar E et al. Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging. Am. J. Neuroradiol.30(5),893–899 (2009).
  Medline CASGoogle Scholar
• 89  Lee JH, Kim SH, Kim GH et al. Identification of pure subcortical vascular dementia using ¹¹C-Pittsburgh compound B. Neurology77(1),18–25 (2011).
  Medline CASGoogle Scholar
• 90  Tomimoto H, Lin JX, Matsuo A et al. Different mechanisms of corpus callosum atrophy in Alzheimer’s disease and vascular dementia. J. Neurol.251(4),398–406 (2004).
  MedlineGoogle Scholar
• 91  Thompson PM, Hayashi KM, De Zubicaray G et al. Dynamics of gray matter loss in Alzheimer’s disease. J. Neurosci.23(3),994–1005 (2003).
  Medline CASGoogle Scholar
• 92  Sydykova D, Stahl R, Dietrich O et al. Fiber connections between the cerebral cortex and the corpus callosum in Alzheimer’s disease: a diffusion tensor imaging and voxel-based morphometry study. Cereb. Cortex17(10),2276–2282 (2007).
  MedlineGoogle Scholar
• 93  Avants BB, Cook PA, Ungar L, Gee JC, Grossman M. Dementia induces correlated reductions in white matter integrity and cortical thickness: a multivariate neuroimaging study with sparse canonical correlation analysis. Neuroimage50(3),1004–1016 (2010).
  MedlineGoogle Scholar
• 94  Agosta F, Pievani M, Sala S et al. White matter damage in Alzheimer disease and its relationship to gray matter atrophy. Radiology258(3),853–863 (2011).
  MedlineGoogle Scholar
• 95  Janowsky JS, Kaye, JA, Carper RA. Atrophy of the corpus callosum in Alzheimer’s disease versus healthy aging. J. Am. Geriatr. Soc.44,798–803 (1996).
  Medline CASGoogle Scholar
• 96  Tomaiuolo F, Scapin M, Di Paola M et al. Gross anatomy of the corpus callosum in Alzheimer’s disease: regions of degeneration and their neuropsychological correlates. Dement. Geriatr. Cogn. Disord.23(2),96–103 (2007).
  Medline CASGoogle Scholar
• 97  Meguro K, Constans JM, Shimada M et al. Corpus callosum atrophy, white matter lesions, and frontal executive dysfunction in normal aging and Alzheimer’s disease. A community-based study: the Tajiri Project. Int. Psychogeriatr.15(1),9–25 (2003).
  MedlineGoogle Scholar
• 98  Rosas HD, Lee SY, Bender AC et al. Altered white matter microstructure in the corpus callosum in Huntington’s disease: implications for cortical ‘disconnection’. Neuroimage49(4),2995–3004 (2010).
  MedlineGoogle Scholar
• 99  Filippini N, Knight S, Talbot K, Turner MR. Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis. Neurology75(18),1645–1652 (2010).
  Medline CASGoogle Scholar
• 100  Yamauchi H, Fukuyama H, Ouchi Y et al. Corpus callosum atrophy in amyotrophic lateral sclerosis. Science134(1–2),189–196 (1995).
  CASGoogle Scholar
• 101  Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Mitra D, O’Brien JT. Diffusion tensor imaging in Alzheimer’s disease and dementia with Lewy bodies. Psychiatry Res.194(2),176–183 (2011).
  MedlineGoogle Scholar
• 102  Wiltshire K, Concha L, Gee M, Bouchard T, Beaulieu C, Camicioli R. Corpus callosum and cingulum tractography in Parkinson’s disease. Can. J. Neurol. Sci.37,595–600 (2010).
  MedlineGoogle Scholar
• 103  Wiltshire K, Camicioli R, Kaye JA, Small BJ. Corpus callosum in neurodegenerative diseases: findings in Parkinson’s disease. Dement. Geriatr. Cogn. Disord.7(6),345–351 (2005).
  Google Scholar
• 104  Zhang Y, Schuff N, Du AT et al. White matter damage in frontotemporal dementia and Alzheimer’s disease measured by diffusion MRI. Brain132(Pt 9),2579–2592 (2009).
  MedlineGoogle Scholar
• 105  Matsuo K, Mizuno T, Yamada K et al. Cerebral white matter damage in frontotemporal dementia assessed by diffusion tensor tractography. Neuroradiology50(7),605–611 (2008).
  MedlineGoogle Scholar
• 106  Agosta F, Henry RG, Migliaccio R et al. Language networks in semantic dementia. Brain133(Pt 1),286–299 (2010).
  MedlineGoogle Scholar
• 107  Tartaglia M, Zhang Y, Racine C, Laluz V. Executive dysfunction in frontotemporal dementia is related to abnormalities in frontal white matter tracts. J. Neurol.259(6),1071–1080 (2012).
  Medline CASGoogle Scholar
• 108  Perry RJ, Graham A, Williams G et al. Patterns of frontal lobe atrophy in frontotemporal dementia: a volumetric MRI study. Dement. Geriatr. Cog. Disord.22(4),278–287 (2006).
  MedlineGoogle Scholar
• 109  Whitwell JL, Jack CR, Senjem ML, Josephs KA. Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration. Neurology66(1),102–104 (2006).
  MedlineGoogle Scholar
• 110  Gazzaniga MS. Forty-five years of split-brain research and still going strong. Nat. Rev. Neurosci.6(8),653–659 (2005).
  Medline CASGoogle Scholar
• 111  Bouma A, Gootjes L. Effects of attention on dichotic listening in elderly and patients with dementia of the Alzheimer type. Brain Cogn.76(2),286–293 (2011).
  MedlineGoogle Scholar