The strength evaluation of adhesively bonded joints having adherends of dissimilar metals bonded with epoxy resin was investigated both analytically and experimentally, in order to establish a method of strength design of adhesive bonding. The strain and stress distributions in the adhesively bonded joints were analyzed by applying the finite element method. The strength of joints was predicted by applying the strength laws to the adherends, adhesive layer and their interfaces. The effects of the mechanical properties of adherends on the joint strength were examined. The analytical strain distributions were in good agreement with the experimental ones. The predicted results of strength coincided approximately with the experimental ones. The smaller the difference in the Young’s modulus between the adherends was, the greater the joint strength was.