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Immunotherapy with Interleukin-2: A Study Based on Mathematical Modeling

International Journal of Applied Mathematics and Computer Science's Cover Image
International Journal of Applied Mathematics and Computer Science
Selected Problems of Computer Science and Control (special issue), Krzysztof Gałkowski, Eric Rogers and Jan Willems (Eds.)

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The role of interleukin-2 (IL-2) in tumor dynamics is illustrated through mathematical modeling, using delay differential equations with a discrete time delay (a modified version of the Kirshner-Panetta model). Theoretical analysis gives an expression for the discrete time delay and the length of the time delay to preserve stability. Numerical analysis shows that interleukin-2 alone can cause the tumor cell population to regress.

ISSN:
1641-876X
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Mathematics, Applied Mathematics