Abstract
The features of the repair processes of DNA damage and their implementation at the chromosome level in marrow cells of experimental animals (mices of the CBA and C3H lines) with different radiation sensitivity were studied. It is shown that the radiomodifying efficiency of moderate hyperthermia (HT) is higher for animals of the radioresyst line. At the same time, it was possible to observe intensive elimination of chromosomal damages, the level of which in later observations almost was not distinguished from the control values. For mices of more radiosensitive lines, a long-term potentiation damaging action of irradiation at the chromosomal level was observed as an additional HT effect.
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Original Ukrainian Text © N.M. Ryabchenko, N.K. Rodionova, I.S. Sychevska, I.I. Muzalev, V.M. Mykhailenko, M.O. Druzhina, 2013, published in Tsitologiya i Genetika, 2013, Vol. 47, No. 1, pp. 50–55.
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Ryabchenko, N.M., Rodionova, N.K., Sychevska, I.S. et al. Genotoxic effects of radiation and hyperthermia in linear mice with different radiation sensitivity. Cytol. Genet. 47, 39–43 (2013). https://doi.org/10.3103/S0095452713010088
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DOI: https://doi.org/10.3103/S0095452713010088