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Phenotypic variability of Arabidopsis thaliana seedlings as a result of inhibition of Hsp90 chaperones

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Abstract

The influence of geldanamycin (GDA)—an inhibitor of Hsp90 chaperones—on the growth and morphogenesis of Arabidopsis thaliana seedlings was studied. It was shown that the treatment of seeds Col with the inhibitor resulted in a dose-dependent increase in the variability of seedling growth rates and phenotypes. GDA treatment of genetic polymorphic seeds of natural A. thaliana populations and UV-B irradiated seeds Col resulted in a significant rise in the amount of nongerminated seeds. The obtained data testify that Hsp90 may restrict stochastic processes, thereby participating in plant development canalization, conceal genetic variations, and maintain cell viability.

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Correspondence to L. E. Kozeko.

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Original Russian Text © L.E. Kozeko, 2013, published in Tsitologiya i Genetika, 2013, Vol. 47, No. 2, pp. 18–33.

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Kozeko, L.E. Phenotypic variability of Arabidopsis thaliana seedlings as a result of inhibition of Hsp90 chaperones. Cytol. Genet. 47, 75–87 (2013). https://doi.org/10.3103/S0095452713020072

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