Analytical Performance of the Commercial MucorGenius® Assay as Compared to an In-House qPCR Assay to Detect Mucorales DNA in Serum Specimens
Abstract
:1. Introduction
2. Materials and Methods
2.1. Clinical Serum Samples
2.2. Specificity Study Using Spiked Serum Samples
2.3. Statistical Analyses
2.4. Ethical Statement
3. Results
3.1. Comparison of qPCR Assays Based on qPCR Positive Serum Samples from Probable and Proven Mucormycosis Patients
3.2. Comparison of qPCR Assays Based on Spiked Serum
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Ghelfenstein-Ferreira, T.; Verdurme, L.; Alanio, A. Analytical Performance of the Commercial MucorGenius® Assay as Compared to an In-House qPCR Assay to Detect Mucorales DNA in Serum Specimens. J. Fungi 2022, 8, 786. https://doi.org/10.3390/jof8080786
Ghelfenstein-Ferreira T, Verdurme L, Alanio A. Analytical Performance of the Commercial MucorGenius® Assay as Compared to an In-House qPCR Assay to Detect Mucorales DNA in Serum Specimens. Journal of Fungi. 2022; 8(8):786. https://doi.org/10.3390/jof8080786
Chicago/Turabian StyleGhelfenstein-Ferreira, Théo, Laura Verdurme, and Alexandre Alanio. 2022. "Analytical Performance of the Commercial MucorGenius® Assay as Compared to an In-House qPCR Assay to Detect Mucorales DNA in Serum Specimens" Journal of Fungi 8, no. 8: 786. https://doi.org/10.3390/jof8080786