Abstract
Limbic system sites from which drinking can be elicited by angiotensin are distributed similarly but not identically to cholinergic drinking sites in the rat. Furthermore, neither cholinergic nor adrenergic blocking agents depress drinking to angiotensin. However, water-deprived, cholinergically stimulated, and angiotensin-stimulated rats show similar sodium chloride preferences. Although the cholinergic and angiotensin systems seem independent, they may both produce a “true thirst.”
Article PDF
Similar content being viewed by others
References
EPSTEIN, A. N., FITZSIMONS, J. T., & SIMONS, B. J. Drinking caused by the intracranial injection of angiotensin into the rat. Journal of Physiology, 1969, 200, 98–100.
FISHER, A. E., & COURY, J. N. Chemical tracing of a central neural circuit underlying the thirst drive. Science, 1962, 138, 691–693.
GIARDINA, A. R., & FISHER, A. E. Effect of atropine on drinking induced by carbachol, angiotensin and isoproterenol. Physiology & Behavior, 1971, 7, 653–655.
LEVITT, R. A., & BOLEY, R. P. Drinking elicited by injection of eserine or carbachol into rat brain. Physiology & Behavior, 1970, 5, 693–695.
LEVITT, R. A., & FISHER, A. E. Anticholinergic blockade of centrally induced thirst. Science, 1966, 154, 520–522.
STELLAR, E., HYMEN, R., & SAMET, S. Gastric factors controlling water- and salt-induced drinking. Journal of Comparative & Physiological Psychology, 1954, 47, 220–226.
STRICKER, E. M., & MILLER, N. E. Saline preference and body fluid analyses in rats after intrahypothalamic injections of carbachol. Physiology & Behavior, 1968, 3, 471–475.
Author information
Authors and Affiliations
Additional information
Supported by USPHS-NIMH Grant MH-14381
Rights and permissions
About this article
Cite this article
White, C.S., Levitt, R.A. & Boyer, S. Drinking elicited by CNS injection of angiotensin in the rat. Psychon Sci 26, 283–284 (1972). https://doi.org/10.3758/BF03328619
Published:
Issue Date:
DOI: https://doi.org/10.3758/BF03328619