A New Drug Vehicle - Lipid Coated Biodegradable Nanoparticles

J. Schäfer; Johannes Sitterberg; C. Ehrhardt; M.N.V. Ravi Kumar; Udo Bakowsky

doi:10.4028/www.scientific.net/AST.57.148

Paper Titles

Fabrication of Titanium Fiber Scaffold for Biomaterial Use
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Fabrication of α-TCP, HAp Functionally Graded Porous Beads
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Addition of Surface Function to Zirconia for Biomaterial Use
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Supramolecular Approach to Gene Delivery
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A New Drug Vehicle - Lipid Coated Biodegradable Nanoparticles
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Base Invaders. Coupling Experiments and Multiscale Modeling of Dendrimer-Based siRNA Delivery Agents
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Trastuzumab Decorated Nanoparticles for Targeted Chemotherapy of Breast Cancer
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Inhibition of Alzheimer Amyloid Aggregation with Sulfate Glycopolymers
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Electrical Field Responsive Polypyrole in Poly(Acrylic Acid) Hydrogel for Transdermal Drug Delivery
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HomeAdvances in Science and TechnologyAdvances in Science and Technology Vol. 57A New Drug Vehicle - Lipid Coated Biodegradable...

A New Drug Vehicle - Lipid Coated Biodegradable Nanoparticles

Abstract:

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.