Effects of Collagen Concentration Variation toward Characteristics of Bacterial Cellulose-Collagen Biocomposites as Candidate of Artificial Dura Mater

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Abstract:

Traffic accident is the highest cause of head injury. In the field of neurosurgery, it is closely related to the defect of duramater (outer layer of the brain). This study aims to perform artificial duramater synthesis from bacteria cellulose that is composited with collagen in order to find the precise composition. Bacteria cellulose was synthesized by fertilizing Acetobacter xylinum bacteria into coconut water. In addition, bacteria cellulose pellicle membrane immersed into collagen solution with various concentration such as 0.4% w/v, 0.5% w/v, 0.6% w/v and 0.7% w/v. The dried sample was characterized by Fourier Transform Infra Red (FTIR), tensile tester, Scanning Electron Microscope (SEM) and swelling test procedure. Result showed that the best sample was ‘Sample A’ (bacteria cellulose-collagen 0.4% w/v) that obtained 8% elongation and 185 μm for the average thickness. Based on the entire result, the biocomposite of bacteria celluose-collagen has a high potential as a candidate of artificial duramater.

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80-87

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July 2017

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