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Synthesis of Silicon- and Carbonate-doped Biomimetic Hydroxyapatite in the Presence of Citrate Ions and its Physicochemical, Bioactivity Properties
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Synthesis of Silicon- and Carbonate-doped Biomimetic Hydroxyapatite in the Presence of Citrate Ions and its Physicochemical, Bioactivity Properties

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Abstract:

The present study investigated the phase composition, the structural, morphological, and bioactivity properties of silicon- and carbonate-doped biomimetic hydroxyapatite synthesized by precipitation from aqueous solutions in the presence of different amounts of citrate ions. The X-ray diffraction and Fourier transform infrared spectroscopy analyses confirmed that all the samples exhibited single-phase. Base on the results of the morphological study, all the obtained samples consisted of porous agglomerated particles made up of tiny crystallites in the nanometer range. The change in structural order, as well as the decrease in particle size and degree of crystallinity result from the presence of citrate ions were revealed by X-ray diffraction, dynamic light scattering, and scanning electron microscopy analyses. Bioactivity properties of samples were studied by analyzing their bioresorbability in physiological saline (ω (NaCl) = 0.9%) and evaluating their solubility in SBF solution after a certain period of soaking time. The amount of the released Ca2+ ions was found to increase with the increasing concentration of citrate ions introduced in the synthesis process. The better solubility of material with the presence of citrate ions was beneficial in the growth of apatite on its surface that made produced material more biocompatible.

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 47 View Preview

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Periodical:

Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 47)

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1-12

DOI:

https://doi.org/10.4028/www.scientific.net/JBBBE.47.1

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Online since:

November 2020

Authors:

Viet Hung Hoang*, Mikhail Aleksandrovich Troubitsin, Liubov Vladimirovna Furda, Thi Tham Hong Nguyen

Keywords:

Bioactivity, Biomaterial, Biomimetic, Citrate Ions, Hydroxyapatite

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