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HomeKey Engineering MaterialsKey Engineering Materials Vol. 695Percutaneous Transpedicular Vertebroplasty versus...

Percutaneous Transpedicular Vertebroplasty versus Conservative Management in Osteoporotic Vertebral Fractures

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Abstract:

Osteoporotic vertebral fractures can lead to late collapse which often cause kyphotic spinal deformity, persistent back pain, decreased lung capacity, increased fracture risk and increased mortality. The purpose of our study is to compare the efficacy and safety of vertebroplasty against conservative management of osteoporotic vertebral fractures without neurologic symptoms. A total of 66 patients with recent OVF on MRI examination were included in the study. All patients were admitted from September 2009 to September 2012. The cohort was divided in two groups: first study group consisted of 33 prospectively followed consecutive patients who suffered 40 vertebral osteoporotic fractures treated by percutaneous vertebroplasty (Group 1), and the control group consisted of 33 patients who suffered 41 vertebral osteoporotic fractures treated conservatory because they reffused vertebroplasty (Group 2). Vertebroplasty with PMMA was performed in 30 patients on 39 VBs, including four thoracic vertebras, 27 vertebras of the thoracolumbar jonction and 8 lumbar vertebras. In the Group 2 were included 30 patients with 39 OVFs (four thoracic vertebras, 23 vertebras of the thoracolumbar junction and 11 lumbar vertebras). In our study on OVF, vertebroplasty delivered superior clinical and radiological outcomes over the first year from intervention when compared to consevative treatment of patients with osteoporotic compression fractures without neurological deficit.

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Biomaterials and Regenerative Biomedicine

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Periodical:

Key Engineering Materials (Volume 695)

Pages:

205-211

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.695.205

Citation:

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Online since:

May 2016

Authors:

Iulian Popa, Petre Matusz, Diana Andrei, Mihai Mardare*, Dan V. Poenaru

Keywords:

Fracture, PMMA, Radiological, Vertebroplasty

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* - Corresponding Author

[1] Alexandru D., So W., Evaluation and Management of Vertebral Compression Fractures. Perm J., 16 (2012) 46–51.

[2] Cauley JA, Thompson DE, Ensrud KC, Scott JC, Black D. Risk of mortality following clinical fractures. Osteoporos Int. 11 (200) 556-561.

DOI: 10.1007/s001980070075

[3] Nevitt MC, Ettinger B, Black DM, Stone K, Jamal SA, Ensrud K, Segal M, Genant HK, Cummings SR. The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med. 128 (1998) 793-800.

DOI: 10.7326/0003-4819-128-10-199805150-00001

[4] Ross PD, Davis JW, Epstein RS, Wasnich RD. Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Ann Intern Med. 114 (1991) 919-923.

DOI: 10.7326/0003-4819-114-11-919

[5] Galibert P, Deramond H, Rosat P, Le Gars D. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. [Article in French] Neurochirurgie, 33 (1987) 166-168.

[6] Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylatevertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. AJNR Am J Neuroradiol. 18 (1997).

[7] Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. RadiolClin North Am. 36 (1998) 533-546.

DOI: 10.1016/s0033-8389(05)70042-7

[8] Duan Y, Seeman E, Turner CH. The biomechanical basis of vertebral body fragility in men and women. J Bone Miner Res. 16 (2001) 2276-2283.

DOI: 10.1359/jbmr.2001.16.12.2276

[9] Myers ER, Wilson SE. Biomechanics of osteoporosis and vertebral fracture, Spine, 22(1997) 25S-31S.

DOI: 10.1097/00007632-199712151-00005

[10] Huskisson E.C., Measurement of pain, Lancet, 2 (1974) 1127-1131.

[11] Buchbinder R., Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C., Graves S., Margaret P.S., Bridie M., A Randomized Trial of Vertebroplasty for Painful Osteoporotic Vertebral Fractures, N Engl J Med 361 (2009) 557-568.

DOI: 10.1056/nejmoa0900429

[12] Kallmes DF, Comstock BA, Heagerty PJ, Judith A. Turner, Wilson DJ, Diamond TH, Edwards R, Gray LA, Lydia Stout, Sara Owen, Hollingworth W, Basavaraj Ghdoke, Deborah J. Annesley-Williams, Ralston SH, Jarvik JG. A Randomized Trial of Vertebroplasty for Osteoporotic Spinal Fractures. N Engl J Med 361 (2009).

DOI: 10.1056/nejmoa0900563

[13] Aebi M., Vertebroplasty: About sense and nonsense of uncontrolled controlled randomized prospective trials, Eur Spine J 18 (2009) 1247-1248.

DOI: 10.1007/s00586-009-1164-9

[14] Wilson D.J., Owen S., Corkill R.A., Facet joint injections as a means of reducing the need for vertebroplasty in insufficiency fractures of the spine, EurRadiol, 21 (2011) 1772-1778.

DOI: 10.1007/s00330-011-2115-5

[15] Alvarez L, Alcaraz M, Pérez-Higueras A, Granizo JJ, de Miguel I, Rossi RE, Quiñones D., Percutaneous vertebroplasty: functional improvement in patients with osteoporotic compression fractures, Spine, 31 (2006) 1113-1118.

DOI: 10.1097/01.brs.0000216487.97965.38

[16] Diamond TH, Champion B, Clark WA. Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. Am J Med. 114 (2003) 257-265.

DOI: 10.1016/s0002-9343(02)01524-3