Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

Ipek Karacan; Innocent Jacob Macha; Gina Choi; Sophie Cazalbou; Besim Ben-Nissan

doi:10.4028/www.scientific.net/KEM.758.120

Paper Titles

Evaluation of Protein Adsorption Capacity of TiO₂-Supported Spherical Porous Hydroxyapatite
p.90

Adhesive Evaluation by Brushing Tests for Hydroxyapatite Films Fabricated on Dentins Using a Water Mist Assisted Er:YAG Laser Deposition Method
p.97

Structural Analysis of Prosthetic Coatings Elaborated by Electrochemical Deposition
p.105

Kinetics and the Theoretical Aspects of Drug Release from PLA/HAp Thin Films
p.113

Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications
p.120

Development of Controllable Simvastatin-Releasing PLGA/β-TCP Composite Microspheres Sintered Scaffolds as Synthetic Bone Substitutes
p.126

Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds
p.132

Preparation and Evaluation of Calcium Sulfate/Collagen Composite Pellets
p.138

Foam-Based Bionanocomposite Scaffold for Bone Tissue Engineering
p.145

HomeKey Engineering MaterialsKey Engineering Materials Vol. 758Antibiotic Containing Poly Lactic...

Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

Abstract:

The biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.

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Periodical:

Key Engineering Materials (Volume 758)

Pages:

120-125

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.758.120

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Online since:

November 2017

Authors:

Ipek Karacan*, Innocent Jacob Macha, Gina Choi, Sophie Cazalbou, Besim Ben-Nissan

Keywords:

Coating Dental Implants, Drug Release Studies, Hard Coral, Hydroxyapatite, PLA Thin Film Composites

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* - Corresponding Author

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