Electrospun Polyvinylpyrrolidone (PVP) Nanofiber Mats Loaded by Garcinia mangostana L. Extracts

Ida Sriyanti; Dhewa Edikresnha; Muhammad Miftahul Munir; Heni Rachmawati; Khairurrijal Khairurrijal

doi:10.4028/www.scientific.net/MSF.880.11

Paper Titles

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Electrospun Polyvinylpyrrolidone (PVP) Nanofiber Mats Loaded by Garcinia mangostana L. Extracts
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HomeMaterials Science ForumMaterials Science Forum Vol. 880Electrospun Polyvinylpyrrolidone (PVP) Nanofiber...

Electrospun Polyvinylpyrrolidone (PVP) Nanofiber Mats Loaded by Garcinia mangostana L. Extracts

Abstract:

Composite nanofibers of polyvinylpyrrolidone (PVP) and Garcinia mangostana L. extract (GME) have been synthesized through electrospinning method for application in drug delivery systems. The precursor solution of 10 mL PVP 10% w/w and GME 2% w/w was then electrospun collected at the rotating collector at the following optimum parameters: a voltage of 15 kV, a collector-nozzle distance of 12 cm, and a flow rate of 1 mL/hour. SEM images showed that the average diameters were 476 nm and 690 nm for the PVP and PVP-GME composite nanofibers, respectively. To some degree, the addition of GME into PVP nanofibers increased the average diameter size of nanofibers. Moreover, the release studies, it was shown that 80% of the GME was released within 30 minutes. Therefore, the PVP-GME composite nanofibers can be applied as the drug delivery systems.

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4th Asia Conference on Mechanical and Materials Engineering

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Periodical:

Materials Science Forum (Volume 880)

Pages:

11-14

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.880.11

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Online since:

November 2016

Authors:

Ida Sriyanti, Dhewa Edikresnha, Muhammad Miftahul Munir, Heni Rachmawati, Khairurrijal Khairurrijal*

Keywords:

Garcinia mangostana L., Nanofibers, Polyvinylpyrrolidone (PVP)

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