Study on Phytoconstituents and Antimicrobial Potential of Sapindus mukorossi Fruit Extract
Versha parcha, Amita Sati, Shivani Dyani
*Email: vershaparcha@gmail.com
Abstract-Sapindus mukorossiis well known for its folk medicinal values. The fruit is valued for the saponins (10.1%) present in the pericarp which constitutes up to 56.5% of the drupe known for inhibiting tumour cell growth. Recently many of the pharmacological actions of this plant have been explored which include the antimicrobial molluscicidal and insecticidal actions.The fruits are of considerable importance for their medicinal value for treating several diseases like excessive salivation,pimples,epilepsy,chlorosis,migranes, eczemaand psoriasis etc.The powdered seeds are employed in the treatment of dental caries, arthritis,commoncold, constipation and nausea. Keeping in view the medicinal importance of the fruit, it was thought worth while to carry out systematic study on phytochemical investigation and antimicrobial potential of fruit extract of Sapindus mukorossi. Fruit were dried, powdered and extracted with different solvent systems with increasing polarity. The extracts were screened for the anti bacterial and antifungal activity. Predominance of antibacterial activity was observed at dose level of 50μg/ml of petroleum ether extract. Maximum zone of inhibition (19mm)&(18mm)was observed against Salmonella typhii and Shigella dysenteria respectively as compared to standard drug Ampicillin 20μg/ml. Since antibacterial activity was observed in 50μg/ml concentration of petroleum ether extract, it was chosen for exploring its antifungal potential also. Maximum zone of inhibition was observed against Aspergillus sulfurous as compared to standard drug ketoconazole 20μg/ml. From the above study, it could be concluded that Sapindus mukorossipetroleum ether fruit extracts(50μg/ml) have good antimicrobial potential and can be explored further to isolate active principlesfrom the same.
