Published September 26, 2019 | Version v1
Software Open

Data and code to reproduce all analyses described in the paper "NicheNet: Modeling intercellular communication by linking ligands to target genes"

  • 1. VIB - Ghent University

Description

Here you can find a directory containing the data and code to reproduce all analyses described in the NicheNet paper (https://www.nature.com/articles/s41592-019-0667-5). 

The subdirectories contain following information:
*networks_final: data and scripts to create the integrated ligand-receptor, signaling and gene regulatory networks
*evaluation_final: data and scripts to validate the NicheNet model. Includes scripts for optimization and characterization of data sources as well.
*application_final: data and scripts used to apply NicheNet to single-cell data from Puram et al. and Medaglia et al.
*data_nichenet_final: final networks, models and expression datasets

Files

application_final.zip

Files (11.5 GB)

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md5:55b00398f6ac46581aebac548b629665
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md5:d04e73c5afa6767c2113ab30c89a1008
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md5:89fb3adc35b09b7ab202fe830f68088c
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Additional details

References

  • Browaeys et al., 2019, Nat. Methods, NicheNet: Modeling intercellular communication by linking ligands to target genes