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Design of the System and Algorithm for the Pattern Analysis of the Bio-Data

바이오 데이터 패턴 분석을 위한 시스템 및 알고리즘 설계

  • 송영옥 (우송대학교 컴퓨터정보학과) ;
  • 김성영 (경북대학교 전기정보컴퓨터공학부) ;
  • 장덕진 (우송대학교 컴퓨터정보학과)
  • Received : 2010.07.15
  • Accepted : 2010.08.09
  • Published : 2010.08.28

Abstract

In the field of biotechnology, computer can play varied roles such as the ordinal analysis, ordianl comparison, nutation tracing, analogy comparison for drug design, estimation of protein function, cell mechanism, and verifying the role of a gene for preventing diseases. Additionally, by constructing database, it can provide an application for the cloning process in other data researches, and be used as a basis for the comparative genetics. For the most of researcher about biotechnology, they need to use the tool that can do all of job above. This study is focused on looking into problems of existing systems to analysis bio data, and designing an improved analyzing system that can propose a solution. In additional, it has been considered to improve the performance of each constituent, and all the constituents, which have been separately processed, are combind in a single system to get over old problems of the existing system.

생명과학 분야에서 컴퓨터를 활용할 수 있는 대표적인 예로는 서열화, 서열화 분석, 비교, 진화, 돌연변이 추적, 약 설계를 위한 유사성 비교, 단백질 기능 예측, 그리고 세포 메커니즘과 질병 발생에서의 유전자 역할 예측 등 다양한 분야를 들 수 있다. 생명공학 연구자들에게는 이와 같은 작업을 위한 도구들이 요구되고 있다. 본 논문에서는 바이오 데이터 분석을 위한 기존 시스템의 문제점을 파악하고, 이를 개선할 수 있는 시스템 설계에 초점을 맞추었다. 또한 각각의 분석 작업을 개선할 수 있고 서로 독립적으로 진행되는 기존의 시스템을 통합할 수 있는 통합 분석 시스템을 설계하고자 한다.

Keywords

References

  1. ETRI(IT-InformationCenter), "bioinformati- cs: Technology & Market Analysis," 2001.
  2. Andreas D.Baxevanis and B. F. Francis Ouellette, Bioinformatics : A Practical Guide to the Analysis of Genes and Proteins, 2000.
  3. James Tisdall, "Beginning Perl for Bioinformatics," 2001.
  4. http://www.ncbi.nlm.nih.gov/Genbank/genbankst ats.html
  5. http://www.genome.ad.jp/dbget/db_growth.html,
  6. http://blast.ncbi.nlm.nih.gov/Blast.cgi
  7. Cynthia Gibas and Per Jambeck, “Developing Bioinformatics Computer Skills,” 2001.
  8. Susumu Goto and Kotaro Shiraishi, "Constructing and Annotating Genes Database in KEGG," International journal of Genome Research, 1998(10).
  9. Andreas D. Baxevanis and B. F. Francis Ouleeltte, "bioinformatics : A paractical Guide to the Analysis of Genes and Proteins," WILEY-INTERSCIENCE, 2001.
  10. W. R. Pearson, "Rapid and sensitive Sequence Comparison with FASTP and FASTA," Methods in Enzymology, 183, pp.63-98, 1990. https://doi.org/10.1016/0076-6879(90)83007-V
  11. Des Higging and Willie Taylor, "Bioinformatics: sequence, structure and databanks," Oxford University Press, 2000.
  12. Pachel Karchin and Richard Hughey, "Weighting Hidden Morkov models for maxinum discrimination," Bioinformatics, Vol.14, 9, 1998. https://doi.org/10.1093/bioinformatics/14.9.772
  13. Dan Pilone, Neil Pitman, "UML 2.0 in a Nutshell," OReilly Media, 2005.
  14. He Ke-qing, Jian Hong, He Fei, and Ying Shi, "Extended UML with role modeling," Wuhan University, 2009.