Undifferentiated carcinoma of the nasopharynx associated with an early paraneoplastic dermatomyositis T1N0M0: About a one case
DOI:
https://doi.org/10.54266/ajo.1.2.60.JFIC4813Keywords:
Dermatomyositis, Paraneoplastic, Nasopharynx, Corticosteroid therapy, RadiotherapyAbstract
Dermatomyositis (DM) is a rare autoimmune disease characterized by non-infectious inflammatory damage to the skin and the predominant muscles in the belts. It is believed to be associated with about one case per 1,000 nasopharyngeal carcinoma (NPC). This association has been described for the locally advanced stage, stage II and stage III of the NPC. Little described in the early stages (stage I), its symptomatology is often indicative of cancer whose diagnosis is based on five criteria: muscle weakness of the proximal limbs, elevation of serum muscle enzymes, histological muscle abnormalities in muscle biopsy, electromyographic abnormality and clinical inflammatory dermatological manifestation. Treatment is based on corticosteroid therapy and etiological treatment of cancer. The prognosis of NPC in patients with paraneoplastic DM is comparable to non-infected patients. We report this case of DM revealing an early stage NPC and we take stock of the state of knowledge about paraneoplastic DM associated with rarely described NPC. Indeed, in Morocco the last description of a case dates back to 2016.
References
Bader-Meunier B, Benveniste O. Dermatomyosite de l’enfant et de l’adulte. 2016 juill. (Protocole National de Diagnostic et de Soins (PNDS)).
Hill CL, Zhang Y, Sigurgeirsson B, Pukkala E, Mellemkjaer L, Airio A, et al. Frequency of specific cancer types in dermatomyositis and polymyositis: a population-based study. The Lancet. janv 2001;357(9250):96‑100. DOI: 10.1016/S0140-6736(00)03540-6
Ziani FZ, Brahmi SA, Najib R, Kanab R, Arifi S, Mernissi FZ, et al. La dermatomyosite paranéoplasique révélant un carcinome indifférencié du nasopharynx: à propos d’un cas. Pan Afr Med J [Internet]. 2016 [cité 28 févr 2024];24. Disponible sur: http://www.panafrican-med-journal.com/content/article/24/29/full/ DOI: 10.11604/pamj.2016.24.29.4822
Chakroun A, Guigay J, Lusinchi A, Marandas P, Janot F, Hartl DM. Paraneoplastic dermatomyositis accompanying nasopharyngeal carcinoma: Diagnosis, treatment and prognosis. European Annals of Otorhinolaryngology, Head and Neck Diseases. juin 2011;128(3):127‑31. DOI: 10.1016/j.anorl.2010.10.007
Vasef MA, Ferlito A, Weiss LM. Nasopharyngeal Carcinoma, with Emphasis on its Relationship to Epstein-Barr Virus. Ann Otol Rhinol Laryngol. avr 1997;106(4):348‑56. DOI: 10.1177/000348949710600416
Toro C, Rinaldo A, Silver CE, Politi M, Ferlito A. Paraneoplastic syndromes in patients with nasopharyngeal cancer. Auris Nasus Larynx. oct 2009;36(5):513‑20. DOI: 10.1016/j.anl.2008.10.006
Maalej M, Ladgham A, Ennouri A, Ben Attia A, Cammoun M, Ellouze R. [The paraneoplastic syndrome in nasopharynx cancer. 32 cases]. Presse Med. 23 févr 1985;14(8):471‑4.
Bohan A, Peter JB. Polymyositis and Dermatomyositis: (First of Two Parts). N Engl J Med. 13 févr 1975;292(7):344‑7. DOI: 10.1056/NEJM197502132920706
Chan HL. Dermatomyositis and Cancer in Singapore. Int J Dermatology. sept 1985;24(7):447‑50. DOI: 10.1111/j.1365-4362.1985.tb05816.x
Hu W han, Chen D lin, Min H qing. Study of 45 Cases of Nasopharyngeal Carcinoma with Dermatomyositis: American Journal of Clinical Oncology. févr 1996;19(1):35‑8. DOI: 10.1097/00000421-199602000-00008
Frikha F, Snoussi M, Salah RB, Saidi N, Kaddour N, Bahloul Z. [Dermatomyositis in the elderly: a study of 4 cases in southern Tunisia]. Pan Afr Med J. 2012;13:26.
Marie I, Mouthon L. Therapy of polymyositis and dermatomyositis. Autoimmunity Reviews. nov 2011;11(1):6‑13. DOI: 10.1016/j.autrev.2011.06.007
Chérin P. [Current therapy for polymyositis and dermatomyositis]. Rev Med Interne. juin 2008;29 Spec No 2:9‑14.
Pautas E, Chérin P, Piette JC, Pelletier S, Wechsler B, Cabane J, et al. Features of polymyositis and dermatomyositis in the elderly: a case-control study. Clin Exp Rheumatol. 2000;18(2):241‑4.
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