Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005, 149(2):221-224 | DOI: 10.5507/bp.2005.030

WHAT ARE ARTIFICIAL NEURAL NETWORKS AND WHAT THEY CAN DO?

Vlastimil Dohnala, Kamil Kučab, Daniel Junb
a Department of Food Technology, Faculty of Agronomy, Mendel University of Agriculture and Forestry, Brno, Czech Republic
b Department of Toxicology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic

The artificial neural networks (ANN) are very often applied in many areas of toxicology for the solving of complex problems, such as the prediction of chemical compound properties and quantitative structure-activity relationship. The aim of this contribution is to give the basic knowledge about conception of ANN, theirs division and finally, the typical application of ANN will be discussed. Due to the diversity of architectures and adaptation algorithms, the ANNs are used in the broad spectrum of applications from the environmental processes modeling, through the optimization to quantitative structure-activity relationship (QSAR) methods. In addition, especially ANNs with Kohonen learning are very effective classification tool. The ANNs are mostly applied in cases, where the commonly used methods does not work.

Keywords: Artificial neural networks, QSAR, Expert systems

Received: June 10, 2005; Accepted: September 25, 2005; Published: December 1, 2005  Show citation

ACS AIP APA ASA Harvard Chicago IEEE ISO690 MLA NLM Turabian Vancouver
Dohnal, V., Kuča, K., & Jun, D. (2005). WHAT ARE ARTIFICIAL NEURAL NETWORKS AND WHAT THEY CAN DO? Biomedical papers149(2), 221-224. doi: 10.5507/bp.2005.030
Download citation

References

  1. Cao Q, Leggio KB, Schniederjans MJ. (2005) A comparison between Fama and Frenchs model and artificial neural networks in predicting the Chinese stock market. Computers & Operations Research 32, 2499-2512. Go to original source...
  2. Pai PF, Hong WC. (2005) Support vector machines with simulated annealing algorithms in electricity load forecasting. Energy Conversion and Management 46, 2669-2688. Go to original source...
  3. Torres M, Hervás C, Amador F. (2005) Approximating the sheep milk production curve through the use of artificial neural networks and genetic algorithms. Computers & Operations Research 32, 2653-2670. Go to original source...
  4. Gagné F, Blaise C. (1997) Predicting the toxicity of complex mixtures using artificial neural networks. Chemosphere 35, 1343- 1363. Go to original source... Go to PubMed...
  5. Dohnal V, Li H, Farková M, Havel J. (2002) Quantitative analysis of chiral compounds from unresolved peaks in capillary electrophoresis using multivariate calibration with experimental design and artificial neural networks. Chirality 14, 509-518. Go to original source... Go to PubMed...
  6. McClelland JL, Rumelhart DE. Explorations in parallel distributed processing. Cambridge, MA: MIT Press, 1988. Go to original source...
  7. Kohonen T. Self-organising maps. New York: Springer, 2001. Go to original source...
  8. Smith PA, Sorich MJ, Low LSC, McKinnon RA, Miners JO. (2004) Towards integrated ADME prediction: past, present and future directions for modelling metabolism by UDP-glucuronosyltransferases. J Mol Graph Model 22, 507-517. Go to original source... Go to PubMed...
  9. Devillers J. (2000) Prediction of toxicity of organophosphorus insecticides against the midge, chironomus riparius, via a QSAR neural network model integrating environmental variables. Toxicology Methods 10, 69-79. Go to original source...
  10. Huuskonen J. (2003) QSAR modeling with the electrotopological state indices: predicting the toxicity of organic chemicals. Chemosphere 50, 949-953. Go to original source... Go to PubMed...
  11. Jouyban A, Majidi M, Jalilzadeh H, Asadpour-Zeynali K. (2004) Modeling drug solubility in water-cosolvent mixtures using an artificial neural network. Il Farmaco 59, 505-512. Go to original source... Go to PubMed...
  12. Valkova I, Vračko M, Basak SC. (2004) Modeling of structure-mutagenicity relationships: counter propagation neural network approach using calculated structural descriptors. Anal Chim Acta 509, 179-186. Go to original source...