We clinically and histopathologically analyzed 16 patients with cement-ossifying fibroma who presented at our department between 1979 and 1998. Women were 75% more likely to develop this lesion than men: the male: female ratio was 1: 3. The average age on presentation of this tumor was 36.6 years, with a range of 14 to 70 years. This tumor arose in the mandible in 11 patients (57.9%) and in the maxilla in 8 (42.1%). Most of the lesions were located in the molar region. Fifteen tumors were surgically removed, and 4 were treated by extirpation. The prognosis of most patients was favorable, and recurrence occurred in only 1 patient (6.7%).