1985 Volume 35 Issue 5 Pages 792-797
The effects of NaF on the growth of Streptococcus mutans (St. mutans) and the activity of dextransucrase purified from St. mutans were examined in vitro. The minimum inhibitory concentrations (MIC) for a fluoride provided as NaF were lower than 180 ppmF without regard to St. mutans serotypes (a-g). NaF arrested bacterial growth at the concentrations of 180 and 360 ppmF bacteriostatically. No effects of fluoride on the synthesis of water-insoluble dextran were observed in the cell-freesystem.