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Additional file 2: of Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

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posted on 2019-03-30, 05:00 authored by Masaya Yasui, Yuki Menjyo, Kyohei Tokizane, Akiko Shiozawa, Makoto Tsuda, Kazuhide Inoue, Hiroshi Kiyama
Figure S1. Expression profile of ATF3-positive neurons in the dorsal root ganglion (DRG). A: ATF3 was hardly observed in the L5 DRG of control rats (NCS). B–F: ATF3-positive neurons in each DRG (L2–6) were observed after 6 days of continuous stress-loading (CS). Scale bar: 200 μm. G: Rates of ATF3-positive cells per section were measured from L5 sections in the NCS group and L2-L5 sections in the CS group. Note that the rate of ATF3 expression peaked in the L5 DRG and was significantly higher than that in the L5 DRG of NCS rats. n = 5. ***p < 0.001. Mann-Whitney U test (PDF 519 kb)

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    Journal of Neuroinflammation

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