Additional file 2: Figure S2. of Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis

Strain differences in the primary visual cortex LFP power in Angelman syndrome model mice. (A, B) Power spectra of group data (WT: n = 30, AS: n = 39; shading indicates ±sem) from the primary visual cortex in C57BL/6 mice. (C, D) Power spectra, measured relative to total power. (E) Raw and (F) relative delta power are not different between WT and AS (raw: p = 0.277, relative: #p = 0.073, Student’s t tests). (G) Raw power in the 3–5-Hz band is not different between WT and AS (#p = 0.077). (H) Relative power in the 3–5-Hz band is significantly increased in AS model mice (**p = 0.0052). (I) Total power (1–50 Hz) is not different between groups (p = 0.460). (J) Raw and (K) relative gamma power are decreased in AS model mice on a C57BL/6 background (raw: *p = 0.022, relative: ***p = 0.00074). (L) Raw and (M) relative beta power are not different between groups (raw: p = .476, relative: p = .166) (PDF 179 kb)