Additional file 3: Figure S2. of Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton’s jelly-derived mesenchymal stem cells (WJ-MSC)

WJ-MSC express PTCH1, the SHH receptor, along with other components of the signaling pathway. PTCH1 was found in WJ-MSC immersed in the Wharton jelly (A,B). (C) PTCH1 was detected in cell lysates from primary cultures, along with positive controls (S2: Saos-2; E.C: endothelial cells; N.T: chicken embryonic neural tube). (D) Expression of other main components of the SHH pathway at mRNA level: SMO, GLI1, GLI2, and GLI3, validated in three independent samples. (TIF 3677 kb)