Research Article | Volume: 7, Issue: 3, March, 2017

Chemical composition and antioxidant activity of extracts from Erythroxylum suberosum A.St. Hil.leaves

Ivelone M. de C. Barros,  Bruno H. M. Leite,  Caio F. M. Leite,  Christopher W. Fagg,  Sueli M. Gomes,  Inês Sabioni Resck,  Yris M. Fonseca-Bazzo,  Pérola O. Magalhães,  Dâmaris Silveira   
Ivelone M. de C. Barros1, Bruno H. M. Leite2, Caio F. M. Leite2, Christopher W. Fagg2, Sueli M. Gomes3, Inês Sabioni Resck4, Yris M. Fonseca-Bazzo1, Pérola O. Magalhães1, Dâmaris Silveira1

1Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

2Faculdade de Ceilândia, Universidade de Brasília, Campus Ceilândia, Centro Metropolitano, conjunto A, lote 01, Brasília, DF, Brazil.

3Departamento de Botânica, Instituto de Ciências Biológicas, Universidade de Brasília,Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

4Instituto de Química. Universidade de Brasilia, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

Open Access   

Published:  Mar 30, 2017

DOI: 10.7324/JAPS.2017.70314
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Abstract

Erythroxylum suberosum A. St. Hill. has been used as anti-rheumatism, anesthetic and for indigestion in Brazilian folk medicine. The crude extracts from leaves were obtained by maceration or infusion. The extracts showed no toxicity to brine shrimp lethality assay. The total phenolics and flavonoids contents were more significant in aqueous and ethanol extracts than its fractions (dichloromethane and hydro-methanol). The antioxidant potential of the crude aqueous extract was, approximately, 4.5 times higher than BHT, while the ethanol extract was 5.9 times. On the other hand, a hydro-methanol fraction from crude ethanol extract was 7.6 times more potent than BHT. Also, it was described the isolation and structural identification of isoquercitrin, rutin, quercetin and isomers catechin and epicatechin, from leaves of E. Suberosum.


Keyword:     Erythroxylum phenolic compounds Cerrado.

Citation:

Barros IMC, Leite BHM, Leite CFM, Fagg CW, Gomes SM, Resck IS, Fonseca-Bazzo YM, Magalhães PO, Silveira D. Chemical composition and antioxidant activity of extracts from Erythroxylum suberosum A.St. Hil.leaves. J App Pharm Sci, 2017; 7 (03): 088- 094.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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